"David Letterman should probably care what women think about him—and not just his wife," said David Bauder in the Associated Press. As if his "crude joke about Sarah Palin's daughter" earlier this year wasn't enough, his bombshell confession that he had sexual relationships with women on his Late Show staff is "likely to hit his reputation hardest with women." And believe it or not, "Letterman's typical audience was 58 percent female last season."

Once "the shock wears off," said Darel Jevens in the Chicago Sun-Times, the Letterman scandal "may not matter." He'll likely maintain female viewers simply by virtue of default: "Even if Letterman falters" temporarily in the ratings, Conan O'Brien "may be too weird to regain the dominance that Leno once had." And Letterman has some influential admirers: "Hollywood beauties from Julia Roberts to Megan Fox have sat in the guest chair and professed longtime crushes on the craggy Hoosier."

Still, CBS and Letterman seem worried, said Rachel Sklar in Mediaite. The network and Letterman's production company, Worldwide Pants, "spent the weekend having 'unauthorized copies'" of Dave's "mea culpa" removed from YouTube. But it's hard to see what they hope to accomplish. Does CBS really "think this toothpaste is going back in the tube?"