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July 2, 2014
NIH Molecular and Clinical Hematology Branch

A small study has shown huge results: Researchers have found that bone marrow transplants can reverse severe sickle cell disease in adults. Out of 30 adult participants, the transplant worked in 26, and one year later 15 were able to go off the anti-rejection pills they were taking.

"We're very pleased," Dr. John Tisdale, the study's senior author and a senior investigator at the National Institutes of Health, told The Associated Press. "This is what we hoped for."

Sickle cell disease is a genetic disorder that damages hemoglobin in red blood cells, which in turn makes them form sickle shapes that can block blood flow. About 100,000 Americans, primarily blacks, have the disease, which can cause organ damage, anemia, and pain, as well as an early death.

The patients participating in the study underwent radiation and chemotherapy to destroy the bone marrow, which was then replaced with healthy marrow cells from a donor, either a patient's brother or sister. The one downside is that less than 1 out of 4 adults with sickle cell disease have a sibling that makes a good match, but researchers are looking into whether other relatives could be suitable donors.

The treatment is a modified version of transplants that have worked in children, whose bodies have yet to be ravaged by the disease. The results of the study were published Tuesday in the Journal of the American Medical Association. Catherine Garcia

May 28, 2016

With 7 in 10 Americans reporting they are "frustrated" with the 2016 presidential election, this year could be the Libertarian Party's big chance — and America's largest third party is holding its national convention in Orlando, Florida, this weekend.

On the agenda: picking a presidential nominee from among three contenders. Though the contest is considered close, greatest name recognition belongs to former New Mexico Gov. Gary Johnson, who was the Libertarian nominee in 2012, when he picked up more than 1 million votes. Johnson recently polled at 10 percent nationally against Hillary Clinton and Donald Trump, and he would need 15 percent support to make it into the general election debates.

You can watch livestream of the convention proceedings below. The nomination is expected to take place around 5 p.m. Eastern on Sunday. Bonnie Kristian

May 28, 2016

Martin Short and Maya Rudolph stopped by The Tonight Show on Friday, so naturally host Jimmy Fallon had to find something totally outlandish for them to do together. The gang spoofed '80s cop shows with The Windy City Blue, a gag that gets progressively sillier — and windier — with each new bit. Hold onto your hat and watch below. Julie Kliegman

May 28, 2016
Yuri Cortez/AFP/Getty Images

The World Health Organization dismissed a call Saturday to move or cancel the Rio Summer Olympics due to the spread of the Zika virus. The U.N. agency was responding to a Friday open letter from 150 health experts urging them to delay or relocate the event "in the name of public health," citing the mosquito-borne virus' link to birth defects.

"Based on the current assessment of the Zika virus circulating in almost 60 countries globally and 39 in the Americas, there is no public health justification for postponing or cancelling the games," the group's statement read.

The Zika virus is thought to have originated in Brazil. Julie Kliegman

May 28, 2016
Chip Somodevilla/Getty Images

Speaking at Harvard University, Federal Reserve Chairwoman Janet Yellen said Friday that she expects to hike interest rates "probably in the coming months" if the economy continues to improve.

Yellen noted that "growth looks to be picking up from the various data that we monitor," referencing rising oil prices and a weaker, stabilizing dollar as the rationale for her decision, which corresponds with recent remarks from other Fed policymakers.

She argued that a gradual increase from the near-zero rate the central bank has maintained since the 2008 financial crisis "would be appropriate" to push inflation toward the Fed's 2 percent goal. Bonnie Kristian

May 28, 2016
Vaughn Ridley/Getty Images

Things are looking good for Cleveland Cavaliers star LeBron James, and not only because he's expected to star in the long-awaited Space Jam sequel.

James scored 33 points Friday in the Cavs' 113-87 rout of the Toronto Raptors. With the win, his team earned a spot in the NBA Finals against either the Oklahoma City Thunder or the Golden State Warriors, which would be a rematch of last year's contest.

This means, as The New York Times reports, that James is set to appear in his sixth-straight NBA Finals, and seventh overall. He's a two-time champ, both from when he took his talents to the Miami Heat. Julie Kliegman

May 28, 2016

Police arrested at least 35 people Friday at a San Diego rally for Donald Trump. About 1,000 people turned out to protest the hard-line immigration policies of the presumptive Republican presidential nominee, Reuters reports.

Clashes between protesters and supporters were largely non-violent, but police in riot gear began pushing and pepper spraying protesters.

Trump's campaign has come under fire for its history of conflict at rallies and its subsequent handling of both protesters and reporters. On Wednesday, police arrested protesters at Trump's Anaheim rally after they reportedly pelted officers with objects. Julie Kliegman

May 27, 2016

A Home Depot employee in Staten Island, New York, sparked death threats by wearing an "America Was Never Great" hat to work, The New York Times reports. Krystal Lake, 22, says she wore the hat after several co-workers wore pro–Donald Trump pins. "The point of the hat was to say that America needs change and improvement," Lake said. A company spokesman said Lake has been told never to wear the hat again. The Week Staff

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