September 20, 2018
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It turns out that an octopus on ecstasy doesn't act all that different than a human on ecstasy.

Scientists who for some reason felt compelled to dunk octopuses into an MDMA solution found that they became more sociable and relaxed, The Atlantic reported Thursday. The Johns Hopkins School of Medicine neuroscientists were surprised to find that the usually solitary and often surly creatures were suddenly interested in befriending their tank-mates and behaving more vulnerably.

Octopuses are extremely intelligent, but their brains are structured differently than those of mammals, neuroscientist Gül Dölen told The Atlantic. Their sophisticated brains are organized "much more like a snail's brain than ours," she said. While the octopuses in the trial were at first independent, a quick bath in an MDMA solution to allow them to absorb the drug through their gills made them willing to interact with one another. The serotonin-releasing amphetamine seemed to cause euphoria just like it does in humans. "They even exposed their [underside], where their mouth is, which is not something octopuses usually do," said Dölen.

The study is just a pilot, but it's still one of the first to show similar drug effects on such dissimilar brains. It provides evidence that serotonin has been an important chemical for social function for millions of years, stretching back to the most recent common ancestor of humans and octopuses, around 800 million years ago. As neuroscientist Robyn Crook told The Atlantic: "There are only so many ways to make an intelligent brain." Summer Meza