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Could weight-loss drugs boost the economy?
Today's Big Question A five-year trial will examine the use of Mounjaro in getting people back to work
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Budget 2024: how will the government raise revenue?
Today's Big Question Rachel Reeves must fill a £22bn fiscal 'black hole' in her first Budget later this month
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Is the UK worth investing in?
Today's big question Labour looks to woo business and reverse years of underinvestment in search for holy grail of growth
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Keir Starmer's first 100 days: how did they go?
Today's big question Honeymoon period dominated by rows over gifts and infighting but there are 'signs of a progressive philosophy emerging'
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What does James Cleverly's shock defeat mean for the Conservatives?
Today's Big Question Tory leadership contest has moved to the right but a 'secret challenger' may lie in wait
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Why does Donald Trump want to free the founder of an online black market?
Today's Big Question Ross Ulbricht was sentenced to life in prison for creating the Silk Road market
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What are the main security threats facing the UK?
Today's Big Question State plots by Russia and Iran are joined by renewed efforts from Islamic State and al-Qaeda, and younger far-right extremists
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How is the House of Lords set to change?
Today's Big Question Parliament's upper chamber faces major reform, starting with Labour's promise to remove remaining hereditary peers
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What's behind Trump's last-minute merch push?
Today's Big Question With just weeks to go before the election, Donald Trump is spending the waning days of his campaign hawking a suite of new products, from silver coins to cryptocurrency
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Israel's wars: is an end in sight – or is this just the beginning?
Today's Big Question Lack of wider strategic vision points to 'sustained low-intensity war' on multiple fronts
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Why are meteorologists worried Trump could ruin their forecasts?
Today's Big Question How a conservative push to dismantle a little-known government agency could lead to big headaches for anyone hoping to get a handle on their local weather
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How could escalation in the Middle East affect the global economy?
Today's Big Question Oil prices have already risen but wider conflict could see supply chains disrupted more broadly
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Can the Conservative Party 'end the squabbling' and win again?
Today's Big Question The Tories have yet to come to terms with their crushing election defeat, say critics
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Will 'weirdly civil' VP debate move dial in US election?
Today's Big Question 'Diametrically opposed' candidates showed 'a lot of commonality' on some issues, but offered competing visions for America's future and democracy
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Why has Iran held back on Israel?
Today's Big Question The Iran-backed Hezbollah has suffered devastating losses to Israel, but Iran has responded 'meekly' so far
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