Two new drugs have been hailed as landmark treatments for Alzheimer's disease – but the NHS won't be rolling them out.

The benefits of lecanemab and donanemab, the first drugs to slow the progress of the disease, are not great enough to justify their high cost, according to the National Institute for Health and Care Excellence, the independent body that decides which medicines should be available on the NHS. Both will be available privately.

How do the new drugs work?
Lecanemab and donanemab are monoclonal antibodies, created in labs to target amyloid beta proteins, which accumulate in clumps, or plaques, in the brain of people with Alzheimer's disease. Delivered through an IV infusion, the drugs bind to the amyloid proteins and then attract the body's own antibodies to attack and break them down. The two drugs operate similarly but lecanemab targets the amyloid proteins as they begin to clump together, while donanemab binds to the proteins once they've clumped together to form larger plaques.

How effective are the new drugs?
Neither drug reverses or stops the disease, but research suggests they could potentially delay the cognitive decline of patients in the early stages of Alzheimer's by between four and seven months. There are some caveats. The benefits seem to be better for men than women and, while the trial participants were generally young, white and with no other health conditions, real-world effectiveness on older, more racially diverse and frailer Alzheimer's patients might be less impressive.

Why are they so expensive?
That's due both to the cost of the drugs themselves and the way they need to be administered. Before starting treatment, an Alzheimer's diagnosis must be confirmed via an expensive scan or lumbar puncture. Then each patient needs an IV infusion every two weeks, along with regular brain scans and check-ups to monitor effectiveness and potential side effects (which are known to include potentially fatal brain swelling and brain bleeds or haemorrhages). These processes effectively double the cost to at least £50,000 per person per year. Approximately 70,000 people in the UK with mild Alzheimer's disease would have been eligible.

It may seem "hard to believe" but Caribbean food has only been "readily available" in Britain's capital since the 1960s, said The Infatuation. Londoners have more than made up for lost time, though. Here are some of the best spots for Caribbean cuisine.

Marvee's Food Shop, Ladbroke Grove
Walking into Marvee's Food Shop is like being transported back in time to a 1970s British-Caribbean living room, with brightly patterned wallpaper, leather chairs and pops of tropical colour. It's a new venture from Dom Taylor, a London-born chef with St. Lucian and Jamaican heritage, but the concept is familiar from his highly successful "The Good Front Room" residency at The Langham's Palm Court. The Food Shop is a tribute to Taylor's mother – the titular Marvee – and the menu feels like a love letter to her influence on his incredible dishes.

LIMIN, Southbank
Breezy and bright, this terrace-style restaurant brings the exciting flavours of Trinidad and Tobago to London's Gabriel's Wharf. Every taste is infused with the heritage and connection that Trinidadian-born chef Sham Mahabir brings to his authentic dishes. The food (pictured above) is second to none, and the service is great too. 

Hoodwood, Kentish Town
Given the name "hood", you might not be surprised that this small Caribbean takeaway has the neighbourhood at its heart. Inside, there's food that packs a real punch. The jerk chicken that is a staple of most Caribbean restaurants is perfectly smoked, while the curry goat is succulent and aromatic. There's an equally excellent vegetarian option with chickpeas, callaloo, jollof rice (traditionally African) and plantain.

It's official: our establishment has lost any sense of right and wrong
Tim Stanley in The Telegraph
Following the votes on abortion and assisted dying, "people keep saying to me" that the state wants to "kill us all to save money", writes Tim Stanley. Joking aside, they feel this way because of "how morally deformed our establishment now is". The biblical command not to take another life may be "inflexible" but "opening morality up to negotiation" that is "contingent upon personality, economics, circumstance", rather than clear notions of right and wrong, "permits evil to flourish".

Getting angry will turn me into a superwoman
Lucy Mangan in The i Paper
"My new hero", writes Lucy Mangan, is Sam Parker, the author of a book called "Good Anger". The "title alone has been enough to blow my tiny mind". That "anger might be allowable" and can even be "channelled as a force for good" is "the most profound, absurd, frightening, liberating" idea "I have ever heard". If all of us "let all our good anger out", we could find ourselves in a "strangely peaceable world".

The art of being an unchill host
Jemima Kelly in the Financial Times
"It cannot be denied" that Donald Trump "understands the importance of throwing a party", writes Jemima Kelly. He has been "mocked" for his "super-duper" military parade and his OTT Mar-a-Lago parties, yet "being in possession of a sense of occasion is a rare thing in our lonely and socially impoverished culture", where gatherings are so often "formulaic and uninspired". Creating a truly memorable occasion means being "brave enough" to be "just a bit unchill".