What happened
A packed funicular tram has derailed in central Lisbon, leaving at least 15 people dead and 18 injured, five critically. The Elevador da Glória, a landmark attraction linking Restauradores with Bairro Alto, smashed into a building yesterday afternoon local time. Authorities said some of the injured were foreign tourists.

Who said what
"Lisbon is in mourning. It's a tragic moment for our city," said Mayor Carlos Moedas. Portuguese President Marcelo Rebelo de Sousa offered his condolences to the victims' families.

Portugal, and Lisbon in particular, "has experienced a tourism boom in the past decade", said The Guardian, "with visitors cramming into the popular downtown area in the summer months". Lisbon hosted about 8.5 million tourists last year and "the streetcar is a popular attraction", said The Independent. "Long lines of tourists typically form for the brief ride on it."

What next?
The government has announced that an investigation will begin once rescue efforts conclude. Questions are mounting over the safety of Lisbon's funicular system, which previously suffered a derailment in 2018, thankfully without any casualties.

What happened
Ground-breaking new research indicates that beta blockers, a class of drugs widely used as a first-line treatment after a heart attack, do not benefit the majority of patients. In fact, women with little heart damage who were treated with beta blockers were significantly more likely to have another heart attack or to be hospitalised for heart failure, and nearly three times more likely to die compared with women not given the drug.

Who said what
The findings "should spark a long-needed, sex-specific approach to treatment for cardiovascular disease", said senior study author Dr Valentin Fuster.

It's "actually not surprising" that women would be more susceptible to harm from beta blockers than men, as "in many cases, women have smaller hearts", said Dr Andrew Freeman, director of cardiovascular prevention at Denver's National Jewish Health.

What next?
The findings only applied to women with normal heart function after a heart attack, noted CNN. Beta blockers "continue to be the standard of care" for anyone with lower heart function due to their ability to calm arrhythmias.

You can earn more than £4,000 for lying in bed for two weeks in a swanky room, with access to free WiFi and food delivered to your door. So say enthusiastic "flu camp" volunteers, who've been recommending the experience on social media.

Obviously, you have to get the flu, too. Volunteers at these clinical trial camps are infected with the virus before being given the trial treatment or a placebo, then monitored over a fortnight to see how their body responds. But is being a human lab rat and spending all that time alone in a room as easy as it sounds?

Once isolated in their room, participants fill in a checklist every morning about their symptoms. "Doctors would come in about four times a day to test your vitals," student volunteer Faith Larkam told Business Insider. "Other than that you're just left to your own devices."

During her stay she "binge-watched movies", read a book "in like three hours", did "a lot of introspection" and "banged out" three or four essays for university.

Exposing volunteers to a controlled dose of a virus in a quarantined setting, rather than running clinical field trials over many years, means that firms can quickly get a "clear picture" of a treatment's efficacy before they move to larger, later-stage studies, according to This Is Money.

And it's certainly proving successful for research firm hVIVO. It finished last year in "rude financial health, with overall revenue up almost 12% at £62.7 million" and a "rock solid" balance sheet "with £44.2 million in cash".