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    CDC chaos, UN resolution and Russian escalation

     
    Today's PUBLIC HEALTH story

    RFK Jr. names new CDC head as staff revolt

    What happened
    Health Secretary Robert F. Kennedy Jr. last night informed Centers for Disease Control and Prevention employees that he had installed his deputy, Jim O'Neill, as acting CDC director, a day after the White House said it had fired Susan Monarez, the recently Senate-confirmed director, at Kennedy's request. Monarez's ouster led three other top CDC officials to quit, and hundreds of CDC staffers gathered to cheer them yesterday as they were escorted from the agency's Atlanta headquarters. 

    Who said what
    CDC staff are "openly revolting" over Monarez's contested firing and "months of tension over vaccine policy and staffing cuts," The Washington Post said. The turmoil has also "triggered rare bipartisan alarm," The Associated Press said. Kennedy "has not explained the decision to oust Monarez," but her lawyers said it was because she refused to "rubber-stamp unscientific, reckless directives and fire dedicated health experts."

    At a meeting Monday, Kennedy ordered Monarez to "agree to accept whatever recommendations were made by the Advisory Committee on Immunization Policy," which he stacked with fellow vaccine skeptics after firing the previous panel, The New York Times said. The White House said it fired Monarez, but President Donald Trump has remained "silent."

    Trump has privately lamented that he "can't take more credit for the Covid vaccine," which he considered "one of the biggest accomplishments of his presidency," said The Wall Street Journal. But he has consistently "had Kennedy's back," and Trump and his "loyalists" have long believed the health secretary helped him win in 2024, Politico said, and that keeping his "MAHA enthusiasts in the GOP tent is crucial to ensuring the party holds onto power in the midterms." Monarez's ouster "proves that no one will provide an effective check on Kennedy — not Republican senators" and "certainly not" Trump, The Washington Post said in an editorial.

    What next?
    Sen. Bill Cassidy (R-La.) said yesterday that Kennedy's vaccine advisory panel's upcoming meeting to craft recommendations for childhood vaccines "should not occur until significant oversight has been conducted," and if it does, "any recommendations made should be rejected as lacking legitimacy."

     
     
    Today's INTERNATIONAL story

    UN votes to end Lebanon peacekeeping mission

    What happened
    The United Nations Security Council yesterday voted unanimously to wind down its peacekeeping mission in Lebanon by the end of 2026, after nearly five decades of operation. The mandate for the U.N.'s Interim Force in Lebanon (UNIFIL), renewed annually since 1978, had been set to expire on Sunday.

    Who said what
    UNIFIL, "initially created to oversee the withdrawal of Israeli troops" after Israel's 1978 invasion, has "played a significant role in monitoring the security situation" in southern Lebanon for decades, said The Associated Press. It has also "drawn criticism from both sides" and from the Trump administration, which views UNIFIL as a "waste of money." Israel considers the U.N. force "toothless," The New York Times said, while Hezbollah, the Iran-backed militant group that has "long dominated" southern Lebanon, sees UNIFIL "as sympathetic to Israel."

    The Trump administration had "pushed for an end to UNIFIL since taking office in January and has already overseen cuts in U.S. funding to the force," Al Jazeera said. But Lebanon and European governments pushed back against a quick dissolution, arguing that Lebanon's military is not yet ready to take over the area, giving Hezbollah a window to regroup from last year's drubbing by Israel.

    What next?
    In January 2027, UNIFIL will begin a yearlong "orderly and safe drawdown and withdrawal" of its 10,800 personnel and equipment from Lebanon, the U.N. said. The goal is to leave "Lebanon fully in charge of southern security." 

     
     
    Today's Russia-Ukraine Story

    Russian strike on Kyiv kills 23, hits EU offices

    What happened
    Russia launched a massive attack on Ukraine yesterday, killing at least 23 people in Kyiv and damaging the European Union's diplomatic office and the nearby British Council office, along with scores of other civilian buildings. Ukraine said it shot down most of the 598 attack drones and 31 missiles Russia fired across the country over 11 hours starting at about 3 a.m. But among the damage was a five-story residential building reduced to rubble. "As of 11 p.m. rescue efforts were still underway," Reuters said.

    Who said what
    Ukrainian President Volodymyr Zelenskyy said the strike, the second-largest since Russia invaded in 2022 and the deadliest since President Donald Trump hosted Russian President Vladimir Putin to jump-start peace talks, showed that Moscow is choosing "ballistics instead of the negotiating table." It was the "clearest signal" since the summit that Putin planned to "eschew Trump's peace efforts" while "also striking a blow to the Western institutions supporting Kyiv," The Wall Street Journal said. 

    Trump "was not particularly perturbed" by "Putin's overnight bombardment," Politico said. He "was not happy about this move, but he was also not surprised," White House press secretary Karoline Leavitt said, equating Russia's "attack on Kyiv," with Ukraine's recent "blow to Russia's oil refineries."

    What next?
    European Commission President Ursula von der Leyen said the EU was preparing a 19th sanctions package to force Putin "to the negotiating table," and vowed that European security guarantees would "turn Ukraine into a steel porcupine."

     
     

    It's not all bad

    A blood test used alongside a trained algorithm could eventually help diagnose ovarian cancer, a disease hard to detect in its early stages due to generalized symptoms like abdominal bloating and pain. The test, developed by AOA Dx, looks for certain lipids and proteins in the bloodstream whose combination is "like a biological fingerprint for ovarian cancer," said The Guardian. In a University of Colorado study, the test was 93% accurate across all stages of ovarian cancer and 91% accurate in early stages.

     
     
    Under the radar

    Scientists are accelerating evolution

    Researchers at Scripps Research Institute have created a new system, T7-ORACLE, that can speed up evolution by 100,000 years, according to a study published in the journal Science. This "directed evolution" is the "process of rapidly evolving proteins, introducing beneficial mutations and selecting advantageous variants," said Popular Mechanics. The "hyper-evolved proteins" can then be used in a "wide variety of potential cancer and neurodegenerative therapies." 

    Previous systems of directed evolution often required "repeated rounds of DNA manipulation and testing, with each round taking a week or more," Scripps said in a press release. However, T7-ORACLE circumvents these challenges by using an engineered E. coli bacterium to host a "second artificial DNA replication system." Essentially, this method operates "separately from the cell's own machinery" and allows its original genome to remain untouched. In turn, scientists can "introduce mutations every time the cell divides (roughly every 20 minutes)."

    Directed evolution is not entirely new. In 2018, Frances Arnold won the Nobel Prize in Chemistry for her work on it. Using Arnold's approach, scientists were able to "'breed' biomolecules, not unlike how farmers breed crops and animals," said Caltech Magazine. 

    There are many promising applications for the new technology. It could be an "important tool for developing new medicines," or "give scientists a better understanding of how antibiotic resistance builds up over time," said Popular Mechanics. Protein evolution can also be used for diagnostic purposes and even to switch diseases off.

     
     
    On this day

    August 29, 2008

    Sen. John McCain (R-Ariz.) chose Alaska Gov. Sarah Palin to be his running mate on the Republican presidential ticket, making her the first female GOP vice presidential nominee. Palin was not the first woman to be nominated, however. That distinction goes to Geraldine Ferraro, Democrat Walter Mondale's running mate in 1984. The first woman vice president was Kamala Harris.

     
     
    TODAY'S newspaperS

    'Uprising at CDC'

    "Standoff at CDC stokes confusion," the Chicago Tribune says on Friday's front page. "CDC reeling as acting director selected," The Atlanta Journal-Constitution says. "CDC chaos under RFK Jr. raises fears about guarding nation's health," The Minnesota Star Tribune says. "Uprising at CDC exposes rifts in president's MAHA alliance," says The Wall Street Journal. "U.S. is taking a hard look at transplants," The New York Times says. "Fed's Cook files lawsuit to challenge her ouster," The Washington Post says. "AI hitting Gen Z's workers already," says the San Francisco Chronicle.

    ► See the newspaper front pages

     
     
    Tall tale

    Put him in, coach

    Topps' latest collectible baseball card features not a player but a squirrel that crashed a New York Yankees game. The squirrel ran onto the Yankee Stadium field during the fourth inning and stared down pitcher Max Fried. "My first reaction was, 'Don't do anything that might embarrass you,'" Fried told MLB.com. The game, against the Boston Red Sox, was paused until the squirrel scurried away and disappeared near the scoreboard area.

     
     

    Morning Report was written and edited by Helen Brown, Nadia Croes, Catherine Garcia, Scott Hocker, Anya Jaremko-Greenwold, Justin Klawans, Rafi Schwartz and Peter Weber, with illustrations by Stephen Kelly and Julia Wytrazek.

    Image credits, from top: Elijah Nouvelage / Getty Images; Awad Awad /AFP / Getty Images; Ed Ram / For The Washington Post via Getty Images; Serg Myshkovsky / Getty Images
     

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