Scientists studying human health may be getting bad information from an unlikely source — their own lab rats. Many rats and mice used for research are fat, out of shape, and "on a trajectory to premature death," according to a report from Johns Hopkins University and the National Institute on Aging. That's a problem, because animals used for research are supposed to be reasonable stand-ins for the average human — when they're chubby and unhealthy, results of experiments designed to shine light on everything from Alzheimer's to cancer can be distorted. Are overfed lab rats useless, or is there still something humans can learn from them?
It's shocking scientists didn't realize using fat rats was stupid: Lab rats eat all day and have little incentive to exercise, says RT.com. "Naturally, these furry versions of coach potatoes balloon." They end up with a skewed metabolism — obviously, a promising drug that works on them "may fail to work, or perform worse on healthy animals."
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