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Autism: Developed in the womb?

Environmental factors may be responsible for more than half of all autism cases, a surprising new study reveals. Researchers who studied about 200 pairs of twins concluded that 58 percent of autism cases arose from conditions encountered in the womb, while 38 percent appeared to be genetic. Scientists had previously thought that about 90 percent of cases were genetic in origin. The finding is “a massive claim” that “flies in the face of the previous data,” Angelica Ronald, a geneticist at the University of London, tells the Los Angeles Times. But other researchers note that autism, which affects 1 in 110 U.S. children, is six times more common now than it was two decades ago—an increase far too rapid for genetic mutation alone to explain. Indeed, a second study published alongside the first shows that women who take antidepressants during their first trimester of pregnancy are three times more likely to have an autistic child than are women who don’t. Other environmental risk factors may include low birth weight, infections contracted in utero, stress, and medications. Researcher Clara Lajonchere says the findings underscore that “prenatal care is critical” to reducing the chances of a child developing autism.

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