Health & Science

Stem cells produce their first cure; How to make fools of men; Blame the potato, not the couch; Building a lunar telescope; Help from a bloodsucker

Stem cells produce their first cure

Stem cells, which can turn into any kind of cell in the body, have been held out as a possible cure for a host of dread diseases. For the first time, says the Los Angeles Times, that promise has been realized in a real patient suffering from an inherited and possibly fatal skin disease. Nate Liao, a 2-year-old from Minneapolis, was born with epidermolysis bullosa, a rare disease caused by the body’s inability to make a key form of collagen, which supports the skin. Nate and his older brother Jake, who also has EB, have skin so delicate that it blisters and falls apart at the slightest touch. Nate and Jake have to wear special clothes and have never eaten solid food; the lining of their esophagus is so fragile that it can only handle liquids. After a plea for help from the boys’ desperate parents, doctors at the University of Minnesota Medical School came up with a plan to give Nate a bone marrow transplant using stem cells harvested from umbilical cord blood. Just a few months later, Nate’s body began making more normal collagen, and his skin is now strong enough for him to wear normal clothes and eat real meals. Nate’s progress has been so encouraging that his parents decided to pursue the treatment for Jake, too. “Nate’s quality of life is forever changed,” says Dr. John Wagner, who performed the transplant. If future treatments are as successful as Nate’s, he says, “maybe we can take one more disorder off the incurable list.’’

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