Study finds stem cell therapy could stop symptoms of MS in some patients
A new study shows that stem cell transplants could stop symptoms in some people with multiple sclerosis, an autoimmune disease that affects 2.3 million patients worldwide.
MS targets the central nervous system, with the immune system attacking the protective sheath covering nerves. During the clinical trial, patients were admitted to the hospital for two weeks, and they had their own stem cells collected and stored. They received high-dose chemotherapy treatments, which wiped out their immune systems. Their stem cells were then infused back into their bodies, giving their immune systems a reboot. Fewer than 10 percent of participants subsequently reported that their condition got worse, versus more than 75 percent of patients whose disease got worse after taking medications for MS over a five-year period.
Dr. Richard Burt, who led the trial at Northwestern School of Medicine, told CBS News: "Transplants ended up being markedly superior in all the perimeters we looked at. You have to select the right group of patients ... there's these really aggressive ones that are very relapsing and inflammatory that it works extremely well in." One of the patients who participated in the trial, Amanda Loy of Alaska, said before the transplant, her arms were numb, she had bladder issues, and her balance was off. Loy has relapsing-remitting MS, and said she can now run, something she couldn't do easily before, and plans on participating in the Chicago Marathon.
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Catherine Garcia is night editor for TheWeek.com. Her writing and reporting has appeared in Entertainment Weekly and EW.com, The New York Times, The Book of Jezebel, and other publications. A Southern California native, Catherine is a graduate of the University of Redlands and the Columbia University Graduate School of Journalism.
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