A man has been declared HIV-free in a case that “upends our understanding of what’s required” for a cure, said The New Scientist.
He was the seventh patient found to be clear of the virus after receiving a stem cell transplant – and, significantly, the second of the seven to receive stem cells that were not actually HIV-resistant. If HIV-resistant cells aren’t necessary to destroy the virus, scientists have greater options in their search for an effective but less risky cure.
Yet even as medics make such leaps forward in HIV/Aids treatment, access to both preventive care and medicine for infected patients “remains far from universal”, said The Guardian.
How close is a cure? The signs are increasingly positive. In addition to the stem-cell study, a separate study published in Nature “shows a glimmer of hope” for controlling HIV without the current daily regimen of pills, said The Washington Post. A small group of patients were given “experimental immunotherapies” and then taken off their pills; the majority were able to keep the virus “at a low level for months” afterwards.
The standard daily antiretroviral therapy has had a “transformative” effect on managing HIV since its nadir of the 1980s. It works by preventing the virus from multiplying in the body. For many people with HIV, their “viral load” becomes so low as to be undetectable, hugely lowering the risk of them transmitting the virus to somebody else. But although antiretrovirals can keep the disease in check, it is not a cure.
How have aid cuts impacted HIV/Aids treatment? Multiple nations are cutting foreign aid funding, on which many lower-income countries depend to deliver health services. This has had a “devastating” impact in the fight against the disease, and on the accessibility of medication, said a UNAids report published to mark World Aids Day, on 1 December.
The cuts made by the US, in particular, have “disrupted HIV/Aids care in many parts of the world”, said NPR. Since Donald Trump began his second presidential term and took an “America First approach”, his administration has slashed international aid programmes. This year was also the first that the US did not formally commemorate World Aids Day.
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