The placebo effect is well known, but researchers from the University of Cincinnati decided to test the theory that patients would respond better to a placebo that they thought had an enormous price tag.
A meta-analysis found that placebos used in clinical trials of Parkinson's treatments improved symptoms by an average of 16 percent, the Los Angeles Times reports, and the University of Cincinnati team decided to study 12 patients with "moderately advanced" Parkinson's in a clinical trial of "a new injectable dopamine agonist." With Parkinson's, patients lose brain cells that make dopamine, something this drug could combat.
The participants were told that they were taking two versions of experimental drugs that worked the same but were made differently, with one costing 15 times more than the other. They were actually given the same exact saline solution. The results showed that both versions of the placebo improved motor function compared with a base line test, but the subjects who took the $1,500 dose had an improvement that was 9 percent greater than the $100-per-dose placebo. "Patients' expectations have an important role in the efficacy of medical therapies," the researchers wrote. The results were published Wednesday in the journal Neurology.
The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.
Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
-
The controversial Free Birth SocietyThe Explainer Influencers are encouraging pregnant women to give birth without midwife care – at potentially tragic cost
-
Wes Anderson: The Archives – ‘quirkfest’ celebrates the director’s ‘impeccable craft’The Week Recommends Retrospective at the Design Museum showcases 700 props, costumes and set designs from the filmmaker’s three-decade career
-
Is conscription the answer to Europe’s security woes?Today's Big Question How best to boost troop numbers to deal with Russian threat is ‘prompting fierce and soul-searching debates’
-
Nobody seems surprised Wagner's Prigozhin died under suspicious circumstancesSpeed Read
-
Western mountain climbers allegedly left Pakistani porter to die on K2Speed Read
-
'Circular saw blades' divide controversial Rio Grande buoys installed by Texas governorSpeed Read
-
Los Angeles city workers stage 1-day walkout over labor conditionsSpeed Read
-
Mega Millions jackpot climbs to an estimated $1.55 billionSpeed Read
-
Bangladesh dealing with worst dengue fever outbreak on recordSpeed Read
-
Glacial outburst flooding in Juneau destroys homesSpeed Read
-
Scotland seeking 'monster hunters' to search for fabled Loch Ness creatureSpeed Read
