10 things you need to know today: September 27, 2012

More than 300 die in Syria's bloodiest day, the NFL reaches a deal with refs, and more in our roundup of the stories that are making news and driving opinion

A protester in New York City holds a sign against Syrian President Bashar al-Assad: On Wednesday bomb attacks and firefights left more than 300 dead in Syria.
(Image credit: Mario Tama/Getty Images)

1. SYRIA'S BLOODIEST DAY LEAVES MORE THAN 300 DEAD

Human rights groups say more than 300 people were killed across Syria on Wednesday, making it the deadliest day of the 18-month-old civil war. Two bombs struck the Syrian army headquarters in Damascus, and gunfire ensued between regime forces and rebel fighters trying to topple President Bashar al-Assad. Outside the capital, at least 40 bodies, including those of women and children, were found in the village of Diabeya. More than 30,000 people have been killed in violence since the revolt began in March 2011. [Telegraph]

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