Right off the bat, the four GOP presidential candidates participating in CNN's early Republican debate Wednesday were asked about frontrunner Donald Trump.

Moderator Jake Tapper asked Louisiana Gov. Bobby Jindal if he "violated Ronald Reagan's 11th Commandment" by speaking ill of a fellow Republican. Jindal said he believes Trump isn't a Republican, and isn't serious about being president. "He'll either implode in the general election, or if God forbid he was in the White House, we wouldn't know what he would do." Former Sen. Rick Santorum (Pa.) struck a more conciliatory tone, saying Trump has "every right to run for president as a Republican," and it doesn't "help when Republicans attack Republicans personally."

Sen. Lindsey Graham (S.C.) was asked why so many of his constituents would rather have Trump as the GOP nominee over him, and responded that at the same time during the 2012 presidential race, Rick Perry and Rudy Giuliani were the Republican frontrunners. Former New York Gov. George Pataki went on the attack against Trump, saying he was not going to be the Republican nominee "period," and added, "This is an important election with an enormous number of challenges facing American people, and the first four questions are about Donald Trump." Trump is "unfit to be president of the United States or the Republican nominee," he said, and failed while running casinos in Atlantic City, New Jersey. "He said he was going to make Atlantic City great again," Pataki said. "Every one of those casinos went bankrupt, and over 5,000 Americans lost their job." Catherine Garcia

Madeleine Westerhout, the former director of Oval Office operations in the Trump administration, has a new book coming out on Tuesday in which she reveals she didn't vote for her old boss in 2016 because his "values didn't seem to align with my own."

But that anecdote apparently didn't bother President Trump, who has a history of rebelling against the books his former aides have written about their time in the White House. Instead, he called the publication a "great new book" and "an honest depiction" of the Trump White House. That's probably because despite her initial skepticism about the president, Westerhout said she soon realized she was wrong and now considers herself a big supporter of the president, even though she lost her job last year.

It's not the first time Trump has brushed off comments from Westerhout. The reason she was fired was because she once boasted to reporters that she believed she had a better relationship with Trump than his own daughters, but Trump called Westerhout a "very good person" and forgave her — though not enough to save her job. Tim O'Donnell

It's time for a geography lesson with President Trump.

During an interview with Fox Sports on Tuesday, the president was asked about the situation in Hong Kong, where in recent months China has cracked down with a new national security law that threatens the city's autonomy, and where Hong Kong authorities arrested media tycoon Jimmy Lai earlier this week. Trump didn't exactly echo his national security adviser, Robert O'Brien, who previously said the U.S. is "deeply troubled" by Lai's arrest. He instead complained Hong Kong had made "a lot of money" the U.S. could have made because of "tremendous incentives."

But he did briefly wade into the political situation, simply to say that it's "a little bit tough from certain standpoints" because, when looking at a map, Hong Kong is "attached to" mainland China. And, well, there's no arguing with that. Tim O'Donnell

Democrats announced the lineup of speakers at next week's Democratic National Convention on Tuesday, and all the usual suspects are included — former President Barack Obama, Sen. Bernie Sanders (I-Vt.), and several ex-presidential candidates, like Sens. Kamala Harris (D-Calif.) and Elizabeth Warren (D-Mass.).

But there's one name missing from the list that has pundits in a tizzy: Susan Rice, the Obama-era diplomat who is reportedly a top pick for vice president.

Presumptive Democratic presidential nominee Joe Biden hasn't announced his runningmate yet, and as he continues to punt the announcement, speculation has been escalating. He's already committed to selecting a woman, and is under some pressure to select a Black woman. But while another top contender, Harris, is listed as a speaker at the DNC, Rice is nowhere to be seen, despite her prominence and renewed spotlight as a VP possibility. Could she be the unnamed "Vice Presidential Nominee" slotted to speak on Wednesday?

It's far from hard evidence, but with analysts hungry for an update in the veepstakes, it's hard to ignore. The DNC is set to begin on Monday, and will largely consist of pre-recorded videos and virtual appearances, to avoid the originally-planned gathering in Milwaukee. Delegates have been asked to stay home, and Biden is expected to accept the nomination from Delaware. Summer Meza

Editor's note: This story has been updated to note Biden's plan to attend the DNC virtually.

President Trump's reasoning for why college football should happen this fall probably wouldn't satisfy a lot of folks in the medical and infectious disease research communities.

The president in an interview with Fox Sports on Tuesday said the season, which is in jeopardy because of the coronavirus pandemic, should be played because COVID-19 'just attacks old people,' especially those with other issues.

It is true that the coronavirus is much more deadly for older people with underlying issues, but young people, even athletes, could get quite sick from the pathogen. Indeed, one of the main reasons the NCAA's so-called 'Power 5 conferences' are contemplating postponing play until, they hope, the spring is because of a rare heart condition called myocarditis that's been linked to COVID-19. Boston Red Sox Eduardo Rodriguez, who contracted the virus, has been sidelined for the entire 2020 Major League Baseball season with the condition, for example. In other words, death is not the only risk. Tim O'Donnell

The Environmental Protection Agency approved a new chemical Monday for use in repelling mosquitos, ticks, and other disease-bearing insects. The newly approved chemical, nootkatone, is a nontoxic oil found in Alaskan yellow cedars (Cupressus nootkatensis) and grapefruits, and it is so aromatic and safe for humans it is used in foods and perfumes. "If you drink Fresca or Squirt, you've drunk nootkatone," Ben Beard, deputy director of the division of vector-borne diseases at the Centers for Disease Control and Prevention, tells The New York Times.

The CDC discovered that nootkatone repels mosquitos, ticks, bedbugs, and fleas, and might also work against lice, sandflies, and other pests, 25 years ago. In high enough concentrations, the oil can kill bugs resistant to synthetic insecticides like DDT and pyrethroids. And it last as long as the synthetic chemicals, unlike other plant-based oils, like citronella and peppermint oil, whose effects wear off after about an hour, says Iowa State University inset toxicology expert Joel Coats. Still, Coats said, his lab has found nootkatone to be "an impressive repellent but a weak insecticide."

The after Oregon State University and CDC scientists discovered the repellant properties of nootkatone, the CDC licensed its patent to a Swiss company, Evolva, the Times reports. Getting EPA approval to use the oil as an active ingredient in insect repellants or insecticides was too expensive a process until the Zika epidemic hit in 2015 and Congress set aside money for mosquito control. That funding "was the key to moving the boulder up the hill," Beard told the Times. Peter Weber

It is mathematically impossible for Kanye West to win the 2020 presidential election, but he is still running — with help from some Republicans who don't appear to be motivated by hopes for a President Kanye. It isn't clear what West is thinking.

West has told Forbes he's fine if his last-minute campaign siphoned votes off from Democrat Joe Biden and helped his friend President Trump win re-election. "I'm not denying it, I just told you," he told Forbes in July. "To say that the Black vote is Democratic is a form of racism and white supremacy." Last Thursday, he told Fobes he is "walking" for president, and when it was pointed out to him that he can only act as spoiler in 2020, West replied: "I'm not going to argue with you. Jesus is King."

Getting on the ballot in all 50 states takes work and expertise, and West has already missed his chances to appear on the ballot in California, Florida, Nevada, Michigan, Pennsylvania, and Illinois. It's not clear his petition for Wisconsin was submitted on time, but it was dropped off by Lane Ruhland, a lawyer whose clients include the Trump campaign, the Republican National Committee, and other GOP candidates.

A GOP-linked law firm submitted West's petition in Ohio, and a longtime GOP operative in Colorado, Rachel George, asked at least one Republican strategist last week: "Would you help me get Kanye West on the ballot in Colorado? No, I am not joking, and I realize this is hilarious," according to an email obtained by Vice News.

It isn't clear if West and his unorthodox Birthday Party will actually help Trump or hurt Biden, but "it's possible" he could tip the election, Nathan Gonzales, editor and publisher of the nonpartisan guide Inside Elections, tells the Los Angeles Times. "We don't know how close the most important states will be. We don't know if he will be on the ballot. And we certainly don't know how many votes he would receive," Gonzales added. "For people to say, 'Oh, Kanye is Black so he'll take Black voters from Biden' is a gross oversimplification of a more complex situation."

Part of the complexity is about West himself. After a bizarre South Carolina rally, West's wife, Kim Kardashian West, pointed to her husband's bipolar disorder and asked for "compassion and empathy." Peter Weber