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  • WeekDay AM: 10 Things you need to know this morning
    US and Iran sign deal, England win thriller, and how parasites could deliver medicine

     
    today’s international story

    US reveals terms of Iran deal as Trump leaves G7

    What happened
    The US and Iran have endorsed a preliminary peace framework that would restore shipping through the Strait of Hormuz, lower barriers to Iranian oil sales and pave the way for a proposed $300 billion reconstruction effort.

    But the memorandum, signed electronically by both countries’ presidents, leaves one of the most contentious issues unresolved for now. Negotiations over Iran’s nuclear activities will continue during a 60-day period, with the option of extending the discussions if both sides agree.

    The framework also envisages an end to military activity in Lebanon and discussions between Iran and Oman over future arrangements for the Strait.

    Who said what
    Donald Trump said the agreement could be formally completed within days, but warned that “if it doesn’t get done in 60 days, that’s all right, we’ll go back to bombing”.

    Trump’s Iran deal is the result of “unrealistic ambitions for an untenable war”, said Andrew Roth in The Guardian. The US “entered the war with maximalist goals and exits it with a pragmatic decision to end conflict despite the political cost”.

    What next?
    The Iran war has “exposed the underlying weaknesses” in American power, said W.J. Hennigan in The New York Times. For Beijing and Moscow, “this evidence of America’s military industrial weakness may catalyse decisions to move forward on their own strategic interests”. According to Becca Wasser, a lead defence analyst with Bloomberg Economics, this “may not be a today problem, but it’s definitely a tomorrow problem”.

     
     
    today’s sport story

    England beat Croatia in World Cup opener

    What happened
    England began their World Cup campaign with a 4-2 victory over Croatia in Dallas, overcoming a shaky first half to pull away after the break in a match that has been hailed as one of the best of the tournament so far.

    Harry Kane struck twice before half-time, including a penalty that had to be retaken after Croatian goalkeeper Dominik Livakovic moved early. Croatia responded on both occasions – through Martin Baturina and Petar Musa – exposing the Three Lions’ defensive weaknesses and leaving the match level at the interval.

    England were better after the restart. Jude Bellingham surged through to score the decisive third goal before Marcus Rashford sealed the result late on as Thomas Tuchel’s side dominated large stretches of the second half.

    Who said what
    Croatia “got Kaned”, said The Sun’s Oli Gamp. “But it wasn’t all plain sailing.” Tuchel’s half-time team talk “fuelled the Three Lions to opening game glory”, said Will Schofield in the Daily Star. The manager’s speech “inspired England to victory after a sloppy first half”, agreed Matt Law in The Telegraph.

    What next?
    The win puts England in a strong early position in Group L, although questions remain about their defending. Croatia were “probably always there for the taking”, said Barney Ronay in The Guardian. “But there was hope here, and energy, and best of all something a little ragged and human.”

     
     
    Today’s Television story

    Clarkson reveals cancer battle on farming show

    What happened
    Jeremy Clarkson was diagnosed with an “aggressive” form of prostate cancer last year. The former “Top Gear” presenter delivered the confronting news during the final episodes of the latest series of “Clarkson’s Farm”, filmed between 2024 and 2025, which aired yesterday.

    Who said what
    Clarkson posted on social media that he usually kept his Amazon Prime Video show “bucolic and charming and cheerful”, but that the latest episodes were “none of those things”. “Sombre news,” he said. “They’re a difficult watch.” He will be out of action “for a while”, but the cancer was detected early and he underwent an operation to remove part of his prostate. “The prostate, 10% of it’s dead,” Clarkson said. “The 10% where the cancer is.”

    It’s clear that “this show has become something else altogether”, said The Independent’s Ellie Harrison. “Yes, there will always be jokes about very small pigs resembling Richard Hammond.” But there will also be “genuinely hard times, too”.

    Clarkson has helped raise “vital awareness”, said Chiara De Biase, fundraising director of Prostate Cancer UK.

    What next?
    Plans are underway for a sixth season of “Clarkson’s Farm”.

     
     

    It’s not all bad

    Archaeologists have uncovered a 5,000-year-old monument near Stonehenge that may have influenced the design of the famous prehistoric site. The structure, discovered at Bulford in Wiltshire, consisted of two large wooden posts aligned with the midsummer sunrise and midwinter sunset. Dating to about 3000BC, it is among Britain’s earliest known solstice monuments. Researchers say it is a “once in a lifetime find” that offers rare insight into the beliefs of Stone Age communities.

     
     
    under the radar

    How hookworms could secrete medicine

    Infecting yourself with internal parasites doesn’t sound like the best way to feel better, but scientists have “engineered” the genes of hookworms to deliver medicine – and “it’s just crazy enough to work”, according to ZME Science.

    US researchers have genetically modified hookworms to produce and secrete specific antibodies. This is a “first step” towards creating “living pharmaceutical factories” that can release therapeutic proteins “directly inside the host”, they said in their study, published in Nature Communications.

    The hookworm has “spent millions of years perfecting how to assure long-term survival inside a human host, and how to get molecules out of its body and into ours”, said senior study author Dr Makedonka Mitreva, from Washington University in St Louis, on science news release site EurekAlert!

    Mitreva and her team used CRISPR gene-editing technology to insert into a hookworm egg genome “a gene coding for an antibody known to counteract” the pufferfish poison tetrodotoxin, a lethal, weaponisable neurotoxin with no known commercial antidote. They then infected hamsters with the modified parasites, and samples taken later showed that the animals had antibodies to tetrodotoxin circulating in their blood.

    “It was like the perfect moment,” Mitreva told R&D World. Now “we can start embarking on hookworms being a two-in-one platform” because we’ve shown that they “can not only deliver a drug, but produce that drug and deliver it”.

    This is an “exciting” approach that “paves the way for all sorts of injection-free biologic drug delivery”, added ZME Science. It’s “tantalising” to think that “engineered hookworms could one day” be our “internal allies, providing continuous therapeutic benefits while living safely within a human host”.

     
     
    on this day

    18 June 2005

    David Tennant made his first appearance as the Tenth Doctor in the BBC’s “Doctor Who” episode “The Parting of the Ways”. This month the BBC announced that it had cancelled the upcoming Christmas special and put the show out to tender. Legendary showrunner Russell T. Davies, who had returned to the programme in 2022, also confirmed on Instagram that he was departing again.

     
     
    Today’s newspapers

    ‘Cabinet coup’

    “Miliband set to trigger cabinet coup”, says the Daily Mail. There are “77,000 voters” who can “change the future of the Labour party – and the country”, says The Independent, as “Makerfield decides”. There are “ten years to save Britain and our Brexit”, says the Daily Express, quoting a warning from Nigel Farage. “England flags face ban by council”, claims the Daily Telegraph. “Starmer sits tight at the G7”, says the Financial Times.

    See the newspaper front pages

     
     
    tall tale

    The best and wurst of times

    A German man has broken the record for making the largest sausage comprised entirely of Lego bricks. Tommy Schmidt used 65,000 individual pieces to construct the two-metre-long sculpture, taking roughly a year to assemble it. He was approached by local sausage manufacturer Die Thüringer for the project, which pays tribute to the region’s local traditions. “Transporting it, however, was a major challenge,” said Schmidt. “From the very beginning I had to plan the model in such a way that it would fit through our large patio door.”

     
     

    Morning Report was written and edited by Arion McNicoll, Harriet Marsden, Will Barker, Ross Couzens and Chas Newkey-Burden, with illustrations by Julia Wytrazek.

    Image credits, from top: Mandel Ngan / AFP / Getty Images; Marvin Ibo Guengoer – GES Sportfoto / Getty Images; Dan Kitwood / Getty Images; Illustration by Julia Wytrazek / Getty Images.

    Morning Report and Evening Review were named Newsletter of the Year at the Publisher Newsletter Awards 2025
     

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