The Food and Drug Administration is sounding the alarm on a widely used narcotic and recommending that steps be taken to restrict its availability. The substance, called 7-hydroxymitragynine, or 7-OH, is a synthetic derivative of the kratom leaf, which is commonly used for pain relief. But unlike kratom, experts say 7-OH has an opioid-like quality, which makes it addictive and easily abused.
'More potent than morphine' The compound is naturally found in the kratom plant, but manufacturers have "isolated and amplified" it to "make a more potent product," said The New York Times. 7-OH is "not a traditional opioid derived from the poppy plant" but has similar addictive attributes and "binds to opioid receptors in the brain," according to scientists.
The substance is increasingly being "added to energy drinks, gummies and supplements sold at gas stations and convenience stores," said The Associated Press. It's also widely available in smoke shops. 7-OH's opioid-like effects make it distinct from standard kratom, and companies that sell kratom have been urging a "crackdown on the products containing 7-OH, portraying it as a dangerously concentrated, synthetic form of the original ingredient."
Kratom is "like a light beer in terms of potency," said Chris McCurdy, a professor of medicinal chemistry at the University of Florida, to Axios. But when 7-OH is extracted from kratom, it becomes "closer to Everclear, the grain spirit that can be 95% alcohol by volume," and "more potent than morphine."
FDA wants 7-OH reclassified The FDA announced that it's urging the Drug Enforcement Agency to "classify 7-OH as a Schedule 1 substance, placing it on a list of drugs that include heroin, lysergic acid diethylamide (LSD) and ecstasy," said The Hill. This would make the drug harder to obtain at locations like gas stations and convenience stores.
The recommendation follows a "thorough medical and scientific analysis by the FDA and is one of several efforts to address the agency's concerns around the growing availability and use of 7-OH opioid products," the FDA said in a press release. The agency is "specifically targeting 7-OH" and is "not focused on natural kratom leaf products."
There have been attempts to regulate the substance before, but they were largely unsuccessful. Government officials, said The Hill, are "prepared to deal with similar pushback again." |