8 recent scientific breakthroughs
From animal communication to new cures for cancer
Scientists are doing research all the time, although a lot of it does not receive immediate attention. New discoveries are always being published, whether the public is aware of it or not — and some even have the potential to change the world as we know it.
1. Panda stem cells
Although giant pandas are no longer considered endangered, they are still a vulnerable species. The good news is that scientists may have found a way to support their survival by taking giant panda skin cells and transforming them into stem cells, according to a study published in the journal Science Advances. The stem cells can then be "nudged into becoming any kind of cell in the body" and "could help researchers breed more giant pandas (Ailuropoda melanoleuca) and develop treatments for their diseases," said Science News.
Stem cells are a "self-renewing, inexhaustible source of material from endangered species, capable of regenerating various cell types as needed," and they "could serve as a crucial tool in preventing species extinction," said the study. Successfully creating the stem cells was a difficult process because researchers have to go "back to the basics" for every animal — and "what worked on humans and mice did not work for pandas," Pierre Comizzoli, a gamete biologist at the Smithsonian's National Zoo, said to The Scientist. While it will still be a while before we see a lab-grown giant panda, scientists want to use the cells to create panda embryos.
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2. Monkey communication
Marmoset monkeys use names to refer to each other, according to a study published in the journal Science. Scientists "recorded spontaneous 'phee-call' dialogues between pairs of marmoset monkeys," said the study. "We discovered that marmosets use these calls to vocally label their conspecifics. Moreover, they respond more consistently and correctly to calls that are specifically directed at them." This type of behavior had only been seen in humans, elephants and dolphins previously. "This is the first time that we have seen this in non-human primates," David Omer, the lead author of the study, said to CNN.
The study raises questions as to whether this form of communication is rare or if it has simply not been researched enough. "I think that as we refine our paradigms and our techniques of acoustic analysis, we will find that many other social animals have more complexity in their communication systems than we currently realize," Con Slobodchikoff, a professor emeritus of biology at Northern Arizona University, said to The Washington Post. "This paper is a good nudge toward us changing our views about animal capabilities and intelligence."
3. Finding the root cause of lupus
Scientists have discovered a cause of lupus and a possible way to reverse it. A study published in the journal Nature points to abnormalities in the immune system of lupus patients that is caused by a molecular abnormality. "What we found was this fundamental imbalance in the types of T cells that patients with lupus make," Deepak Rao, one of the study authors, said to NBC News. Specifically, "people with lupus have too much of a particular T cell associated with damage in healthy cells and too little of another T cell associated with repair," NBC News said.
The good news is that this could be reversed. A protein called interferon is mainly to blame for the T-cell imbalance. Too much interferon blocks another protein called the aryl hydrocarbon receptor, which helps regulate how the body responds to bacteria or environmental pollutants. In turn, too many T-cells are produced that attack the body itself. "The study found that giving people with lupus anifrolumab, a drug that blocks interferon, prevented the T-cell imbalance that likely leads to the disease," said NBC News.
4. Restoring brain cells
Scientists have found a way to repair brain cells impaired by a rare genetic disorder. A study published in the journal Nature found that a drug called antisense oligonucleotide allowed human neurons to develop normally despite carrying a mutation due to a genetic disorder called Timothy syndrome. "It's the beginning of a new era for many of these diseases that we first thought were untreatable," Dr. Huda Zoghbi, a professor at Baylor College of Medicine, said to NPR.
Timothy syndrome is caused by a mutation of a single gene in a person's DNA. The new drug develops an "antisense nucleotide, a small piece of synthetic genetic material that alters the proteins made by a cell," said NPR. The antisense nucleotide for Timothy syndrome was designed to replace a defective protein with a healthy version — "in effect counteracting the mutation responsible for the disorder." This same approach could potentially be used to treat other genetic disorders, "including some that cause schizophrenia, epilepsy, ADHD and autism spectrum disorder."
5. Menstrual blood as a diagnostic tool
Menstrual blood can potentially be used to measure blood sugar. In early 2024, the U.S. Food and Drug Administration (FDA) approved a new diagnostic menstrual pad called the Q-Pad and A1C Test by the biotechnology research company Qvin. The Q-Pad is an organic cotton period pad that "collects the blood, which a laboratory then uses to analyze the individual's average blood sugar over three weeks through the A1C biomarker," said Forbes.
"There is a lot of clinically relevant information in this bodily fluid that comes every month," Sara Naseri, the CEO and co-founder of Qvin, said to Axios. "We've built a way for women to get insights about their health regularly. Non-invasively, using blood that comes every month, the menstrual blood." Diagnostic capabilities can potentially be extended to diagnose HPV or endometriosis.
6. Cell therapy for melanoma
The U.S. Food and Drug Administration (FDA) approved the first cellular therapy for aggressive forms of melanoma. The treatment, called Amtagvi, is "designed to fight off advanced forms of melanoma by extracting and replicating T cells derived from a patient's tumor," said NPR. These cells are also called tumor-infiltrating lymphocytes (TIL). T cells are integral in the immune system but can become "dysfunctional inside tumors."
"The approval of Amtagvi represents the culmination of scientific and clinical research efforts leading to a novel T cell immunotherapy for patients with limited treatment options," Dr. Peter Marks, the director of the FDA's Center for Biologics Evaluation and Research, said in a statement. The treatment won't work for everyone, but research by the National Institutes of Health showed a "56% response rate among patients with melanoma, and 24% of patients had a complete disappearance of their melanoma, regardless of where it was," Axios said. "This is the tip of the iceberg of what TIL can bring to the future of medicine," Patrick Hwu, the CEO of Moffitt Cancer Center, said to Axios.
7. Rhino IVF
Scientists were able to impregnate a southern white rhino using in-vitro fertilization (IVF). Researchers in Kenya implanted a southern white rhino embryo into another of the same species using the technique in September 2023, resulting in a successful pregnancy. The technique could be used to save the northern white rhino from total extinction. "We achieved together something which was not believed to be possible," Thomas Hildebrandt, the head of the reproduction management department at the Leibniz Institute for Zoo and Wildlife Research, said in a press conference.
There are two species of white rhinos: northern and southern. The northern white rhino is on the verge of extinction due to poaching, with only two females remaining. Luckily, scientists have sperm preserved from the last male rhino, which could be combined with an egg from the female and implanted into a southern white rhino female to act as a surrogate. Using a white rhino embryo to test the procedure was a "proof of concept" which is a "milestone to allow us to produce northern white rhino calves in the next two, two and a half years," Hildebrandt said.
8. Pristine configuration
Scientists discovered six exoplanets that revolve around a star in a rare pattern called orbital resonance, said a study published in the journal Nature. This means that "for every six orbits completed by planet b, the closest planet to the star, the outermost planet g completes one," CNN said, adding that "as planet c makes three revolutions around the star, planet d does two, and when planet e completes four orbits, planet f does three."
The system was deemed a "rare fossil" by Rafael Luque, a postdoctoral scholar in the University of Chicago's Department of Astronomy and Astrophysics. "We think only about one percent of all systems stay in resonance," Luque said in a statement. "It shows us the pristine configuration of a planetary system that has survived untouched." The discovery could help further the study of sub-Neptunes, which are planets larger than Earth but smaller than Neptune. They are not present in our solar system. "There is little agreement among astronomers about how these planets form and what they're made of — so an entire system consisting of sub-Neptunes could help scientists determine more about their origin," Luque said.
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Devika Rao has worked as a staff writer at The Week since 2022, covering science, the environment, climate and business. She previously worked as a policy associate for a nonprofit organization advocating for environmental action from a business perspective.
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