Novavax says its COVID-19 vaccine prevents severe cases from U.K., South African variants


Novavax announced Thursday that its COVID-19 vaccine had proved effective, especially at preventing serious illness or death, in late-stage trials in Britain and South Africa, home to two of the more contagious variants spreading around the world.
The Maryland biotech firm said that its final analysis of its British trial found the vaccine 96 percent effective against the original strain and 86 percent effective against the B.1.1.7 variant, for an overall protection rate of 90 percent. In the smaller South African trial, the vaccine was 55 percent effective at preventing COVID-19 cases among people without HIV, and 49 percent effective when the HIV-positive subset was included. There were zero cases of severe illness in either country among trial participants who got the vaccine, Novavax said, versus 10 severe cases in people given placebos.
"A trend we're seeing, even with these variants, is that these vaccines are retaining high efficacy against severe disease," Kathleen Neuzil, director of the Center for Vaccine Development and Global Health at the University of Maryland School of Medicine, tells The Washington Post. "I really loved seeing the 100 percent efficacy against severe disease."
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.

Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
The results, mostly in line with a preliminary analysis from January, have not yet been peer-reviewed or published. But Novavax says it will submit them to regulatory agencies around the world, including in Britain and the U.S. The company expects its 30,000-person trial in the U.S. and Mexico to wrap up by early April. If the Food and Drug Administration accepts the data from the U.K. study, Novavax says, its vaccine could get U.S. approval as soon as May. Otherwise, it could be several months before the U.S. gives it the green light.
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Peter has worked as a news and culture writer and editor at The Week since the site's launch in 2008. He covers politics, world affairs, religion and cultural currents. His journalism career began as a copy editor at a financial newswire and has included editorial positions at The New York Times Magazine, Facts on File, and Oregon State University.
-
Samsung to make Tesla chips in $16.5B deal
Speed Read Tesla has signed a deal to get its next-generation chips from Samsung
-
FCC greenlights $8B Paramount-Skydance merger
Speed Read The Federal Communications Commission will allow Paramount to merge with the Hollywood studio Skydance
-
Tesla reports plummeting profits
Speed Read The company may soon face more problems with the expiration of federal electric vehicle tax credits
-
Dollar faces historic slump as stocks hit new high
Speed Read While stocks have recovered post-Trump tariffs, the dollar has weakened more than 10% this year
-
Economists fear US inflation data less reliable
speed read The Labor Department is collecting less data for its consumer price index due to staffing shortages
-
Crypto firm Coinbase hacked, faces SEC scrutiny
Speed Read The Securities and Exchange Commission has also been investigating whether Coinbase misstated its user numbers in past disclosures
-
Starbucks baristas strike over dress code
speed read The new uniform 'puts the burden on baristas' to buy new clothes, said a Starbucks Workers United union delegate
-
Warren Buffet announces surprise retirement
speed read At the annual meeting of Berkshire Hathaway, the billionaire investor named Vice Chairman Greg Abel his replacement