John Oliver tackles America's opioid and heroin crisis, and boy is he mad at Big Pharma


"I would like to talk to you about drugs," John Oliver said on Sunday's Last Week Tonight, but not in some 1960s "reefer madness" way. "Unfortunately, America is now in the midst of a new drug crisis, and it seems that no one is safe from it," he said. That would be the "epidemic of addiction to opioids, like heroin and prescription painkillers," he said, and it's a serious one: As of 2015, an estimated 2.6 million Americans were addicted to these drugs, and some 30,000 Americans die from overdoses each year from heroin and prescription opioids.
Oliver focused on the prescription variety, the chemical cousins of heroin that some 75 percent of U.S. heroin addicts started their addiction with. Now, according to the U.S. surgeon general, some 250 million opioid prescriptions are written each year, equal to one for each adult. It wasn't always this way — as recently as the early 1990s, doctors were "excessively wary" about prescribing these powerful, addictive drugs, Oliver said. And it wasn't just Big Pharma — patient advocates argued that excessive fear of opioids was causing injured and dying people too much pain. But when Perdue — maker of OxyContin — and other drug companies got involved in the late 1990s, he said, all hell broke loose.
After discussing Perdue's shady marketing and downplaying of addiction risk, Oliver said we "may be glad to hear that in 2007 they admitted some responsibility," paying out $634 million. "But at a certain point, the question has to become less 'What did we do wrong?' and more 'What do we do now?'" Oliver said. "There is no one simple answer here." We need to be more careful about prescribing opioids and make alternative treatments more widely available, he said, but "not all opioid addicts will respond to the same treatments, and not all people in pain will find relief from alternative therapies. This is going to take a massive effort and a significant investment — it won't be cheap, it won't be quick, and it won't be easy. And it is hard not to be angry at the drug companies, like Purdue, whose promise of cheap, quick, easy pain solution helped put us in this f---ing mess." Watch below, and be warned, that last F-bomb isn't bleeped out. Peter Weber
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.

Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
Sign up for Today's Best Articles in your inbox
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Peter has worked as a news and culture writer and editor at The Week since the site's launch in 2008. He covers politics, world affairs, religion and cultural currents. His journalism career began as a copy editor at a financial newswire and has included editorial positions at The New York Times Magazine, Facts on File, and Oregon State University.
-
Today's political cartoons - March 30, 2025
Cartoons Sunday's cartoons - strawberry fields forever, secret files, and more
By The Week US Published
-
5 hilariously sparse cartoons about further DOGE cuts
Cartoons Artists take on free audits, report cards, and more
By The Week US Published
-
Following the Tea Horse Road in China
The Week Recommends This network of roads and trails served as vital trading routes
By The Week UK Published
-
Tesla Cybertrucks recalled over dislodging panels
Speed Read Almost every Cybertruck in the US has been recalled over a stainless steel panel that could fall off
By Justin Klawans, The Week US Published
-
Crafting emporium Joann is going out of business
Speed Read The 82-year-old fabric and crafts store will be closing all 800 of its stores
By Peter Weber, The Week US Published
-
Trump's China tariffs start after Canada, Mexico pauses
Speed Read The president paused his tariffs on America's closest neighbors after speaking to their leaders, but his import tax on Chinese goods has taken effect
By Peter Weber, The Week US Published
-
Chinese AI chatbot's rise slams US tech stocks
Speed Read The sudden popularity of a new AI chatbot from Chinese startup DeepSeek has sent U.S. tech stocks tumbling
By Peter Weber, The Week US Published
-
US port strike averted with tentative labor deal
Speed Read The strike could have shut down major ports from Texas to Maine
By Peter Weber, The Week US Published
-
Biden expected to block Japanese bid for US Steel
Speed Read The president is blocking the $14 billion acquisition of U.S. Steel by Japan's Nippon Steel, citing national security concerns
By Peter Weber, The Week US Published
-
Judges block $25B Kroger-Albertsons merger
Speed Read The proposed merger between the supermarket giants was stalled when judges overseeing two separate cases blocked the deal
By Peter Weber, The Week US Published
-
Rupert Murdoch loses 'Succession' court battle
Speed Read Murdoch wanted to give full control of his empire to son Lachlan, ensuring Fox News' right-wing editorial slant
By Peter Weber, The Week US Published