Parkinson's might get its start in your appendix, study suggests
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
You are now subscribed
Your newsletter sign-up was successful
What started off as one scientist's "weird idea" has become a full-fledged scientific study, and its results suggest the appendix may determine whether someone gets Parkinson's disease.
In the generally useless gut organ, there's an abnormal buildup of neurotoxic proteins that often slide their way to the brain, Stat News reports. That protein's appearance in the brain is an indicator of Parkinson's, and a study published Wednesday found that people who've had their appendix removed have a lower risk of getting the disease.
Researchers launched the study based on findings that, of 1.6 million Swedes, those who'd had an appendectomy were 19.3 percent less likely to develop Parkinson's. They also noted how the appendix was full of the Parkinson's-linked protein, per Stat. While this doesn't mean the appendix can directly cause Parkinson's — people without appendixes still get the disease — it is another "piece of the puzzle" in finding what does, a Parkinson's expert tells The Associated Press.
The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.
Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
Parkinson's affects the brain, causing tremors throughout the body. But scientists have long known the disease is connected to the gastrointestinal system. People tend to develop GI issues before getting the brain disease, and cutting the nerve that links the appendix to the brain has also reduced Parkinson's chances, AP says.
Still, the study does note that 99 percent of people don't end up getting Parkinson's, even though most of them have the intestinal organ, reports Stat. Likewise, there was no benefit to losing an appendix once the roots of Parkinson's had already taken hold, or for those who lived in urban environments. So you can call off that preventative appendectomy, at least for now. Read more at Stat News.
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Kathryn is a graduate of Syracuse University, with degrees in magazine journalism and information technology, along with hours to earn another degree after working at SU's independent paper The Daily Orange. She's currently recovering from a horse addiction while living in New York City, and likes to share her extremely dry sense of humor on Twitter.
