Wenger's Arsenal party could end in tears at Chelsea

Premier League preview: Liverpool and Man City will pop corks for Wenger if he downs Mourinho

Arsene Wenger, AC Milan v Arsenal

ARSENAL boss Arsene Wenger will be centre of attention this weekend as he marks his 1,000th game in charge of the Gunners. If he celebrates with a win, or even a draw against fellow title chasers Chelsea, he will be not just the toast of Islington, but also the red part of Liverpool and the blue half of Manchester, as it would seriously undermine the Blues' hopes of winning the Premier League. On a weekend when the other two teams in the title race, Liverpool and Man City, will expect to claim victories over relegation candidates, another slip-up by the league leaders, who lost last week against Aston Villa, would put the cat among the pigeons. Further down the table, Spurs will be looking to hold on to fifth place, but they are under serious pressure from Everton and Man United could force their way back into the European scrap with victory over West Ham. Here's the best of the weekend action: Chelsea v Arsenal

There is a danger that sentimentality will cloud people's judgement of what will happen at Stamford Bridge on Saturday lunchtime. Yes, it is Arsene Wenger's 1,000th game in charge of Arsenal and the club will be desperate to mark it with some kind of success. However, ten of his previous 999 games have been against teams managed by Jose Mourinho and so far none have ended in victory for the Frenchman. What's more, Arsenal have failed to beat Chelsea, Man City or Man United in any of their last 11 attempts, and who could forget that Chelsea have never lost a home game in the Premier League under Mourinho? If injury-ravaged Arsenal do win on Saturday it will be remembered for more reasons than Wenger's milestone. However, a better bet would be a pound or two on Wenger to be banished to the stands. The odds on that are a generous 100-1, and a combination of Mourinho's goading, another injury to a key player and the end of the Gunners' title hopes could push the Nutty Professor over the edge. Man City v Fulham

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