This drug might help teeth repair their own cavities

A drug designed to treat Alzheimer's disease could also be the key to cutting back on trips to the dentist for dreaded cavity fillings. In a study published in the journal Scientific Reports, scientists revealed the drug, called tideglusib, has been found to "stimulate the tooth to create new dentine capable of filling in large cavities," The Independent reported.
Teeth naturally have the ability to repair small areas of damage, but scientists say this drug enhances that ability, making it possible for "the tooth's own cells to rebuild cavities extending from the surface to the root," The Guardian said. All dentists would have to do, scientists suggest, is prep the tooth the same as they would for a filling, then insert a biodegradable sponge soaked in the drug into the tooth, which would then be sealed up. After a few weeks, the sponge would degrade and the cavity would be filled in by dentine.
Before you get too excited about saying sayonara to fillings, note that this is far from a done deal. Scientists have successfully tested the technique in mice teeth, but they're not yet entirely certain it will work on human teeth, which are much larger and thus tend to have much larger cavities.
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.

Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
Sign up for Today's Best Articles in your inbox
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
-
Today's political cartoons - April 20, 2025
Cartoons Sunday's cartoons - Pam Bondi, retirement planning, and more
By The Week US
-
5 heavy-handed cartoons about ICE and deportation
Cartoons Artists take on international students, the Supreme Court, and more
By The Week US
-
Exploring the three great gardens of Japan
The Week Recommends Beautiful gardens are 'the stuff of Japanese landscape legends'
By The Week UK
-
China accuses NSA of Winter Games cyberattacks
speed read China alleges that the U.S. National Security Agency launched cyberattacks during the Asian Winter Games in February
By Rafi Schwartz, The Week US
-
Russian strike kills dozens in Ukraine
Speed Read The Sumy ballistic missile strike was Russia's deadliest attack on civilians this year
By Peter Weber, The Week US
-
Inside the Israel-Turkey geopolitical dance across Syria
THE EXPLAINER As Syria struggles in the wake of the Assad regime's collapse, its neighbors are carefully coordinating to avoid potential military confrontations
By Rafi Schwartz, The Week US
-
South Korea court removes impeached president
Speed Read The Constitutional Court upheld the impeachment of Yoon Suk Yeol after his declaration of martial law in December
By Peter Weber, The Week US
-
Myanmar quake deaths rise as survivor search intensifies
speed read The magnitude-7.7 earthquake in central Myanmar has killed a documented 2,000 people so far, and left scores more trapped beneath rubble
By Peter Weber, The Week US
-
'Like a sound from hell': Serbia and sonic weapons
The Explainer Half a million people sign petition alleging Serbian police used an illegal 'sound cannon' to disrupt anti-government protests
By Abby Wilson
-
Israel detains director after West Bank settler clash
speed read The director of Oscar-winning documentary 'No Other Land' was arrested and beaten
By Rafi Schwartz, The Week US
-
Turkey arrests Istanbul mayor, a top Erdogan rival
Speed Read Protests erupted in Turkey after authorities detained Istanbul Mayor Ekrem Imamoglu
By Peter Weber, The Week US