The potential benefits of an 'intranasal' COVID vaccine

Nasally-administered vaccine.
(Image credit: TIM SLOAN/AFP via Getty Images)

Get those tissues ready.

A COVID-19 vaccine that's nasally administered — rather than shot into the arm — could provide heightened upper respiratory protection, Stat News reported Tuesday.

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Moreover, an intranasal vaccine wouldn't require a syringe, cutting both cost and medical waste, nor would it likely necessitate an administering health care professional, writes Stat. Plus, an intranasal inoculation is usually easier to offer to young kids and those with a fear of needles.

All that said, the development of such a tool might be far off. It's not yet clear if the mRNA vaccines could be reformulated, and an intranasal candidate is likely to be a "next, next, next-gen vaccine," adds Florian Krammer, a vaccinologist at the Icahn School of Medicine at Mount Sinai Hospital. Funding is reportedly also an issue.

"It may be possible but would take a lot of work and may require some new innovations," said Barney Graham, who led the team at the National Institute of Allergy and Infectious Diseases that designed the Moderna vaccine. "There are other groups working on it."

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Brigid Kennedy

Brigid Kennedy worked at The Week from 2021 to 2023 as a staff writer, junior editor and then story editor, with an interest in U.S. politics, the economy and the music industry.