Scientists have sequenced the Ebola genome


An international team of scientists has sequenced the RNA of 99 samples of the Ebola virus, collected during the outbreak's early days in Sierra Leone.
Samples were collected from 78 patients, with some giving twice so researchers could see how the virus mutates in a person. "The genome sequence of a virus is the blueprint on which that virus is built," Pardis Sabeti, a Harvard geneticist who helped oversee the study, told the Los Angeles Times. "Diagnostics are built on knowing that sequence; vaccines are also built using genome sequences. And if you want to build those as best you can, you want to know what the virus looks like today."
Scientists are taking a close look at the sequence, searching for clues that could lead them to effective vaccines or drugs. They've discovered that the Ebola virus that has killed more than 1,500 people originated in Guinea, with one transmission from an animal to a human. The sequencing started in early June, and by mid-June the results were available to scientists. "We want to enable everyone in the scientific community to look at the genetic sequences at once and crowd-source a solution," Sabeti said.
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.

Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
It's personal now for the researchers, as five of the study's co-authors in Sierra Leone have died of Ebola since participating in the research. "It's been an emotional time for us," said Stephen Gire, a research scientist and co-leader of the study. "It makes us want to work harder to get this information out there."
The findings were published Thursday in the journal Science.
Sign up for Today's Best Articles in your inbox
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Catherine Garcia has worked as a senior writer at The Week since 2014. Her writing and reporting have appeared in Entertainment Weekly, The New York Times, Wirecutter, NBC News and "The Book of Jezebel," among others. She's a graduate of the University of Redlands and the Columbia University Graduate School of Journalism.
-
RFK Jr. scraps Covid shots for pregnant women, kids
Speed Read The Health Secretary announced a policy change without informing CDC officials
-
New FDA chiefs limit Covid-19 shots to elderly, sick
speed read The FDA set stricter approval standards for booster shots
-
US overdose deaths plunged 27% last year
speed read Drug overdose still 'remains the leading cause of death for Americans aged 18-44,' said the CDC
-
Trump seeks to cut drug prices via executive order
speed read The president's order tells pharmaceutical companies to lower prescription drug prices, but it will likely be thrown out by the courts
-
RFK Jr. visits Texas as 2nd child dies from measles
Speed Read An outbreak of the vaccine-preventable disease continues to grow following a decade of no recorded US measles deaths
-
Shingles vaccine cuts dementia risk, study finds
Speed Read Getting vaccinated appears to significantly reduce the chances of developing Alzheimer's and other forms of dementia
-
Measles outbreak spreads, as does RFK Jr.'s influence
Speed Read The outbreak centered in Texas has grown to at least three states and Health Secretary Robert F. Kennedy Jr. is promoting unproven treatments
-
RFK Jr. offers alternative remedies as measles spreads
Speed Read Health secretary Robert F. Kennedy Jr. makes unsupported claims about containing the spread as vaccine skepticism grows