Scientists develop compound that can kill antibiotic-resistant superbugs


British scientists say they have discovered a new compound that can kill antibiotic-resistant bacteria, including E. coli.
The compound was developed by Kirsty Smitten, a doctoral student at the University of Sheffield, and researchers are testing it on gram-negative bacteria that is resistant to antibiotics. Prof. Jim Thomas said since the compound is luminescent and glows when exposed to light, advanced microscope techniques allow researchers to follow the "uptake and effect on bacteria. .... This breakthrough could lead to vital new treatments to life-threatening superbugs and the growing risk posed by antimicrobial resistance."
Gram-negative bacteria can cause infections that are hard to treat because the cell walls are difficult to penetrate. Health organizations are concerned about the rise of more drug-resistant superbugs, and it's estimated that by 2050, more than 10 million people could die annually from antibiotic-resistant infections, ScienceDaily reports. There hasn't been a new treatment for gram-negative bacteria in five decades, and the next stage in this research is to test the compound against additional multi-resistant bacteria.
The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.

Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Catherine Garcia has worked as a senior writer at The Week since 2014. Her writing and reporting have appeared in Entertainment Weekly, The New York Times, Wirecutter, NBC News and "The Book of Jezebel," among others. She's a graduate of the University of Redlands and the Columbia University Graduate School of Journalism.
-
10 concert tours to see this upcoming fall
The Week Recommends Get ready for pumpkin spice season with concerts from big-name artists
-
How to put student loan payments on pause
The Explainer If you are starting to worry about missing payments, deferment and forbearance can help
-
Is Kash Patel’s fate sealed after Kirk shooting missteps?
TODAY'S BIG QUESTION The FBI’s bungled response in the immediate aftermath of the Charlie Kirk shooting has director Kash Patel in the hot seat
-
SpaceX breaks Starship losing streak in 10th test
speed read The Starship rocket's test flight was largely successful, deploying eight dummy satellites during its hour in space
-
Rabbits with 'horns' sighted across Colorado
speed read These creatures are infected with the 'mostly harmless' Shope papilloma virus
-
Lithium shows promise in Alzheimer's study
Speed Read Potential new treatments could use small amounts of the common metal
-
Scientists discover cause of massive sea star die-off
Speed Read A bacteria related to cholera has been found responsible for the deaths of more than 5 billion sea stars
-
'Thriving' ecosystem found 30,000 feet undersea
Speed Read Researchers discovered communities of creatures living in frigid, pitch-black waters under high pressure
-
New York plans first nuclear plant in 36 years
Speed Read The plant, to be constructed somewhere in upstate New York, will produce enough energy to power a million homes
-
Dehorning rhinos sharply cuts poaching, study finds
Speed Read The painless procedure may be an effective way to reduce the widespread poaching of rhinoceroses
-
Breakthrough gene-editing treatment saves baby
speed read KJ Muldoon was healed from a rare genetic condition