A nationwide study that's been submitted to the New England Journal of Medicine found that hydroxychloroquine — a malaria drug often touted by President Trump has a strong candidate for COVID-19 therapy — does not benefit coronavirus patients, The Associated Press reports.
In fact, the analysis, which tracked 368 patients in U.S. veterans hospitals, shows that patients treated with the drug actually died at a higher rate than those treated with standard care. Hydroxychloroquine reportedly also didn't make a difference when it comes to who needed a breathing machine.
The study was the largest to look at the drug so far, but like its predecessors, it still isn't considered a rigorous experiment and has yet to be peer-reviewed. The National Institutes of Health and other research labs are in the process of conducting large-scale trials that will hopefully paint a clear picture of its efficacy. Still, several scientists have been "underwhelmed" with the drug's performance so far. Read more at The Associated Press. Tim O'Donnell
At least 18 people were killed and 57 injured Saturday during a suicide bombing in Kabul, Afghanistan, the interior ministry said. The casualty toll may rise as family members continue searching hospitals where the wounded are being treated.
The explosion occurred outside an education center in Dasht-e-Barchi, a heavily Shiite neighborhood in the western section of the capital, per The Associated Press. No group has claimed responsibility for the attack, and the Taliban — which has begun peace talks with the Afghan government amid an ongoing, decades-long conflict that has seen a recent surge in violence — rejected any involvement. The Islamic State said it was behind a similar attack that killed 34 students at an education center in 2018, but there has been no word from the militant group regarding the most recent incident.
Also on Saturday, one roadside bomb killed nine people in eastern Afghanistan, and a second killed two policemen after it struck their vehicle en route to the site of the first explosion. Again, no one claimed responsibility, although a spokesman for the provincial police claimed the Taliban had placed the explosives, AP reports. Read more at The Associated Press. Tim O'Donnell
Biden promises increased scientific investment if elected in 'most in-depth statement of priorities'
The State Department on Friday temporarily halted "all training programs related to diversity and inclusion," Reuters reports.
Reuters obtained an internal cable detailing the decision, which was made in response to an executive order issued by President Trump in September forbidding federal agencies to teach "divisive concepts" such as the idea that the United States is "fundamentally racist or sexist." Before that, the White House Office of Management and Budget sent a memo telling government officials they couldn't use taxpayer money to fund sessions focused on subjects like critical race theory or white privilege. The Trump administration's efforts to cut back on such programs comes amid a nationwide debate about racial injustice in the U.S. — both contemporarily and historically — which was fueled in large part by protests against police brutality earlier this year.
The State Department cable said the pause will allow the OMB "to review program content." Per Reuters, a report from an independent federal watchdog released this year said "longstanding diversity issues exist" in the State Department, particularly in senior ranks. The report noted that the overall proportion of racial or ethnic minorities working at the agency has increased, but the proportions of Black and female employees have declined. Read more at Reuters. Tim O'Donnell
Coronavirus vaccine trials conducted by AstraZeneca and Johnson & Johnson are preparing to resume, the pharmaceutical companies said Friday.
Both studies were put on hold after two volunteers who enrolled in AstraZeneca's vaccine trial developed a possible neurological side effect, and another person enrolled in J&J's study reportedly suffered a stroke. AstraZeneca, which had already restarted its trial in other parts of the world, including the United Kingdom, South Africa, and Brazil, said independent monitoring committees and international regulators agreed it was safe to resume the trial in the U.S, as well. The Food and Drug Administration reportedly did not find the vaccine candidate to be responsible for the neurological symptoms, but the agency was also unable to definitively rule out a link.
Similarly, investigators concluded the J&J volunteer's illness did not appear to be related to the vaccine candidate, although there was "no clear cause" of the incident. Paul Stoffels, the chief scientific officer at J&J, told Stat News the company could begin enrolling patients for the vaccine study — the only major one to test just a single dose — again early next week. Read more at The Washington Post and The Wall Street Journal. Tim O'Donnell
Polish President Andrzej Duda tested positive for the coronavirus Friday, a presidential minister said Saturday. Duda is the latest among a handful of world leaders, including President Trump, to contract the virus. He reportedly "feels good" and is in isolation. Poland's president guides foreign policy and signs legislation, but most duties designated for the office are ceremonial, and day-to-day governance is the responsibility of the prime minister.
Duda's positive test result comes amid a wave of infections in Poland, which saw low rates earlier this year when the virus first struck Europe. On Saturday, the country recorded 13,628 new COVID-19 cases and 179 deaths, marking new 24-hour highs since the pandemic began. The government imposed new restrictions Saturday that fall just short of a lockdown in the hopes of curbing the outbreak, The Associated Press reports.
The virus continues to surge in other European countries, as well, including the Czech Republic, Belgium, the Netherlands, Switzerland, and France. Those five countries currently have the highest rate of infection worldwide, CNN reports.
Italy and Spain, which were hit hard by the virus early in the pandemic, are also dealing with case increases. Several regions in Spain have announced new night curfews in the coming days, while the governor of Italy's Campania said he is imposing a regional lockdown "for 30 to 40 days" after the country reported a daily record of infections Friday. Read more at The Associated Press and CNN. Tim O'Donnell
The United States on Friday recorded more than 85,000 new coronavirus cases, The New York Times reports. That set a new single-day record, breaking the previous mark from mid-July by nearly 10,000 cases. Hospitalizations have also been rising steadily since the start of October, and while deaths have mostly remained flat, they are often a lagging indicator.
The current surge is most heavily concentrated in the Midwest and West, but it's spread out more widely than the previous waves from the spring and summer, which occurred primarily in the Northeast and Sun Belt, respectively. More than 170 counties across 36 states were designated rapidly rising hotspots, an internal federal report produced Thursday for Department of Health and Human Services officials that was obtained by The Washington Post revealed.
Earlier in the pandemic, health care workers would move around to help ease the burden facing overwhelmed hospitals, but "that's just not possible when the virus is surging everywhere," Eleanor Murray, an epidemiologist at Boston University, told the Post; experts have warned of shortages of medical staff and supplies.
Additionally, Murray said, "we are starting this wave much higher than either of the previous waves. And it will simply keep going up until people and officials decide to do something about it." Read more at The Washington Post and The New York Times. Tim O'Donnell