Gene-editing technique used to fight influenza could 'neutralize' coronavirus
![Gene editing.](https://cdn.mos.cms.futurecdn.net/vmHzZ6Zk7DBs4maksLU2XN-415-80.jpg)
PAC-MAN might be the key to munching our way through the coronavirus pandemic.
Okay, so the ghost-eating yellow blob has nothing to do with stopping a deadly virus. But a gene editing technique that borrows the video game's name could prove effective in "scrambling" COVID-19's genetic code and stopping it from growing, Science Daily reports.
Stanley Qi's bioengineering team at Stanford University started working last year to develop a way to use the CRISPR gene-editing tool to fight influenza, calling their technique "PAC-MAN." It sends a virus-killing enzyme into a virus' RNA — DNA's instructional messenger — that in turn tells the enzyme to attack the virus' genetic material.
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.
![https://cdn.mos.cms.futurecdn.net/flexiimages/jacafc5zvs1692883516.jpg](https://cdn.mos.cms.futurecdn.net/flexiimages/jacafc5zvs1692883516-320-80.jpg)
Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
The arrival of the novel coronavirus, with no clear cure or treatment, presented a new opportunity for PAC-MAN. "By scrambling the virus's genetic code, PAC-MAN could neutralize the coronavirus and stop it from replicating inside cells," Science Daily writes.
But there was still the dilemma of how to actually deliver the PAC-MAN technique into lung cells. So after publishing a preprint of their study on the technique, Qi's lab found the Biological Nanostructures Facility at Berkeley Lab's Molecular Foundry. The facility focuses on using lipitoids to deliver therapies, and after a first test, the lipitoids "performed very well" at delivering the gene-scrambling treatment, Science Daily writes. Read more at Science Daily.
Create an account with the same email registered to your subscription to unlock access.
Sign up for Today's Best Articles in your inbox
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Kathryn is a graduate of Syracuse University, with degrees in magazine journalism and information technology, along with hours to earn another degree after working at SU's independent paper The Daily Orange. She's currently recovering from a horse addiction while living in New York City, and likes to share her extremely dry sense of humor on Twitter.
-
The lab-made meat that 'could kill the EU'
Under The Radar Concerned at 'unintended consequences for farming' some farmers are 'turning rabid' over the rise of cultured meat
By Chas Newkey-Burden, The Week UK Published
-
Magazine solutions - August 2, 2024
Puzzles and Quizzes Issue - August 2, 2024
By The Week Staff Published
-
Magazine printables - August 2, 2024
Puzzles and Quizzes Issue - August 2, 2024
By The Week Staff Published
-
Texas dairy worker gets bird flu from infected cow
Speed Read The virus has been spreading among cattle in Texas, Kansas, Michigan and New Mexico
By Peter Weber, The Week US Published
-
Dengue hits the Americas hard and early
Speed Read Puerto Rico has declared an epidemic as dengue cases surge
By Peter Weber, The Week US Published
-
US bans final type of asbestos
Speed Read Exposure to asbestos causes about 40,000 deaths in the U.S. each year
By Peter Weber, The Week US Published
-
Seattle Children's Hospital sues Texas over 'sham' demand for transgender medical records
Speed Read Texas Attorney General Ken Paxton subpoenaed records of any Texan who received gender-affirming care at the Washington hospital
By Peter Weber, The Week US Published
-
Afghanistan has a growing female suicide problem
Speed Read The Taliban has steadily whittled away women's and girls' rights in Afghanistan over the past 2 years, prompting a surge in depression and suicide
By Peter Weber, The Week US Published
-
US life expectancy rose in 2022 but not to pre-pandemic levels
Speed Read Life expectancy is slowly crawling back up
By Devika Rao, The Week US Published
-
Vallance diaries: Boris Johnson 'bamboozled' by Covid science
Speed Read Then PM struggled to get his head around key terms and stats, chief scientific advisor claims
By The Week UK Published
-
An increasing number of dog owners are 'vaccine hesitant' about rabies
Speed Read A new survey points to canine vaccine hesitancy
By Devika Rao, The Week US Published