5 reasons experts are optimistic about Pfizer's coronavirus vaccine. 3 reasons why they're cautious.


Science and health experts are bullish on the news about the Pfizer and BioNTech coronavirus vaccine candidate.
The main reason for the excitement is the vaccine looks like it's on pace to fly right past the Food and Drug Administration's 50 percent efficacy threshold, according to its interim analysis, which pegged the rate at 90 percent so far. There's more good news between the lines, though — the companies say they haven't observed any safety concerns among trial volunteers, the immune response should last for up to a year, and it's unlikely any mutations would be able to overcome the immune response.
The analysis looks promising for Pfizer's competitors, as well, since many other candidates are targeting the same protein on the virus. Plus, if the technology behind the vaccine is successful against COVID-19, it could open a realm of possibilities for vaccine development, at large.
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.

Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
That said, there are reasons to temper expectations, which, after all, are based on a press release. The 90 percent efficacy rate could drop as the trial continues (additionally, safety concerns could arise and the questions about immunity length and mutation protection remain open-ended), and there's also a lack of clarity about whether the vaccine may protect against the most severe COVID-19 cases and whether it protects elderly people. Tim O'Donnell
Sign up for Today's Best Articles in your inbox
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Tim is a staff writer at The Week and has contributed to Bedford and Bowery and The New York Transatlantic. He is a graduate of Occidental College and NYU's journalism school. Tim enjoys writing about baseball, Europe, and extinct megafauna. He lives in New York City.
-
Trump's actions cut a wide swath across Hawaii's economy
In Depth The state's tourism and farming sectors are two of the largest hit industries
By Justin Klawans, The Week US Published
-
5 immersive books to read this April for a brief escape
The Week Recommends A dystopian tale takes us to the library, a journalist's ode to her refugee parents and more
By Theara Coleman, The Week US Published
-
'The winners and losers of AI may not be where we expect'
Instant Opinion Opinion, comment and editorials of the day
By Justin Klawans, The Week US Published
-
Shingles vaccine cuts dementia risk, study finds
Speed Read Getting vaccinated appears to significantly reduce the chances of developing Alzheimer's and other forms of dementia
By Peter Weber, The Week US Published
-
Measles outbreak spreads, as does RFK Jr.'s influence
Speed Read The outbreak centered in Texas has grown to at least three states and Health Secretary Robert F. Kennedy Jr. is promoting unproven treatments
By Peter Weber, The Week US Published
-
RFK Jr. offers alternative remedies as measles spreads
Speed Read Health secretary Robert F. Kennedy Jr. makes unsupported claims about containing the spread as vaccine skepticism grows
By Peter Weber, The Week US Published
-
Texas outbreak brings 1st US measles death since 2015
Speed read The outbreak is concentrated in a 'close-knit, undervaccinated' Mennonite community in rural Gaines County
By Rafi Schwartz, The Week US Published
-
Mystery illness spreading in Congo rapidly kills dozens
Speed Read The World Health Organization said 53 people have died in an outbreak that originated in a village where three children ate a bat carcass
By Peter Weber, The Week US Published
-
Ozempic can curb alcohol cravings, study finds
Speed read Weight loss drugs like Ozempic and Wegovy may also be helpful in limiting alcohol consumption
By Peter Weber, The Week US Published
-
New form of H5N1 bird flu found in US dairy cows
Speed Read This new form of bird flu is different from the version that spread through herds in the last year
By Peter Weber, The Week US Published
-
Microplastics accumulating in human brains, study finds
Speed Read The amount of tiny plastic particles found in human brains increased dramatically from 2016 to 2024
By Peter Weber, The Week US Published