Merck, one of the world's most storied vaccine makers, is abandoning the development of its two COVID-19 vaccines after initial trials resulted in inadequate immune responses, Stat News reports. Both vaccines produced lower levels of coronavirus antibodies than have been found in the blood of individuals who recovered from natural COVID-19 infections. For reference, the Pfizer-BioNTech and Moderna vaccines produced antibody levels several times higher than natural infections.
The unsuccessful trials are disappointing in large part because both Merck vaccines would have required just one dose, writes Stat. One of the candidates, which uses the same virus as the one in Merck's successful Ebola vaccine, was being developed in partnership with the International AIDS Vaccine Initiative, which has said it will try to determine if using an oral or intranasal administration route will work better than the current intramuscular injection. It's unclear if Merck will continue to collaborate — IAVI's president Mark Feinberg told Stat he hopes they do — because the pharmaceutical company has suggested it will now turn its focus to developing COVID-19 therapeutics.
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.
Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
-
The student loans fraud scandalThe Explainer Huge amounts of money may have been fraudulently claimed from the Student Loans Company
-
Is this the end of democracy in Turkey?Today's Big Question President Erdoğan's jailing of political rival a 'decisive moment' that moves country toward full-fledged autocracy
-
How the government's welfare reforms could affect youThe Explainer Labour is attempting to balance the books with £5bn of benefits cuts
-
RFK Jr. offers alternative remedies as measles spreadsSpeed Read Health secretary Robert F. Kennedy Jr. makes unsupported claims about containing the spread as vaccine skepticism grows
-
Texas outbreak brings 1st US measles death since 2015Speed read The outbreak is concentrated in a 'close-knit, undervaccinated' Mennonite community in rural Gaines County
-
Mystery illness spreading in Congo rapidly kills dozensSpeed Read The World Health Organization said 53 people have died in an outbreak that originated in a village where three children ate a bat carcass
-
Ozempic can curb alcohol cravings, study findsSpeed read Weight loss drugs like Ozempic and Wegovy may also be helpful in limiting alcohol consumption
-
New form of H5N1 bird flu found in US dairy cowsSpeed Read This new form of bird flu is different from the version that spread through herds in the last year
-
Microplastics accumulating in human brains, study findsSpeed Read The amount of tiny plastic particles found in human brains increased dramatically from 2016 to 2024
-
FDA approves painkiller said to thwart addictionSpeed Read Suzetrigine, being sold as Journavx, is the first new pharmaceutical pain treatment approved by the FDA in 20 years
-
Study finds possible alternative abortion pillSpeed Read An emergency contraception (morning-after) pill called Ella could be an alternative to mifepristone for abortions
