Former FDA commissioner explains why a 'plan B' is needed in places using Oxford vaccine

Scott Gottlieb.
(Image credit: Screenshot/Twitter/CBS)

Former Food and Drug Administration Commissioner Scott Gottlieb told CBS News' Margaret Brennan on Sunday that there needs to be a "plan B" in areas where the COVID-19 vaccine developed by the University of Oxford and AstraZeneca is widely used.

The problem is, Gottlieb explained, the most logical replacement shot — the Johnson & Johnson candidate (which isn't on the market yet) — may be rendered ineffective in people who have already taken the Oxford vaccine since both rely on adenoviruses to draw an immune response. Gottlieb clarified that the latter point is not proven, but the risk is there until data becomes clear. In that case, he said the answer may be to turn to the vaccines that use mRNA technology, such as those developed by Pfizer and Moderna, instead, but they present significant distribution challenges. Tim O'Donnell

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Tim O'Donnell

Tim is a staff writer at The Week and has contributed to Bedford and Bowery and The New York Transatlantic. He is a graduate of Occidental College and NYU's journalism school. Tim enjoys writing about baseball, Europe, and extinct megafauna. He lives in New York City.