Moderna to start clinical trials of booster shot that targets COVID-19 variant

A vial of the Moderna vaccine.
(Image credit: Ronny Hartmann/AFP via Getty Images)

Moderna announced on Wednesday it will begin testing a new version of its COVID-19 vaccine designed to target the coronavirus variant first reported in South Africa.

The pharmaceutical company said it has sent doses of the booster shot to the U.S. National Institutes of Health for clinical trials. In a statement, CEO Stéphane Bancel said Moderna is "committed to making as many updates to our vaccine as necessary until the pandemic is under control."

Moderna previously revealed that preliminary studies showed the vaccine still made neutralizing antibodies above protective levels for the South African variant, but because it was a reduced level, it prompted the company to begin tweaking the vaccine against the strain, as well as variants that first spread in the United Kingdom and Brazil.

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Moderna is already conducting tests involving giving a third dose of its original vaccine as a booster to people who have received two doses, and the new clinical trials will evaluate the safety of the variant-specific booster and a "multivalent booster candidate" that is one dose of the variant-specific booster and original vaccine, NBC News reports.

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Catherine Garcia

Catherine Garcia is night editor for TheWeek.com. Her writing and reporting has appeared in Entertainment Weekly and EW.com, The New York Times, The Book of Jezebel, and other publications. A Southern California native, Catherine is a graduate of the University of Redlands and the Columbia University Graduate School of Journalism.