Health & Science

Our bodies, our microbes; The folly of Bonnie and Clyde; An oasis on Titan; Cougars headed to the Midwest

Our bodies, our microbes

Our bodies contain 10 times more bacteria than human cells, and those resident microbes may rule our mental and physical health. That’s the conclusion of researchers who for the first time have mapped up to 99 percent of the microbes that live, more helpfully than harmfully, in the human body. Using DNA sequencing on samples gathered from 242 healthy volunteers, they discovered that we each host 100 trillion bacteria of 10,000 types. As much as six pounds of our body weight is bacteria. Each person has a unique microbiome, or balance of different types of microbes. “These microbes are part of our evolution,” New York University microbiologist Martin Blaser tells NPR.org. “They are very important in human health and probably human disease as well.” Helpful bacteria assist in the digestion of food, train the immune system, and aid in keeping harmful bacteria from taking root. Researchers hope that maps of healthy microbiomes will allow doctors to identify bacterial imbalances that can cause infections, mood disorders, obesity, and other medical problems—and offer clues on how tweaking a patient’s microbial makeup could address them. The next challenge, Washington University biologist George Weinstock says, is to figure out how microbes “talk to our human cells” and how “human cells talk back to them.” That conversation, he says, “makes us who we are.”

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