Study finds that antidepressants quickly change the brain's structure


A new study published Thursday in the journal Current Biology found that antidepressants work faster than previously thought, despite the fact that it usually takes patients at least two weeks to report any changes in mood.
More than one in 10 U.S. adults use SSRIs, which block the reabsorption of serotonin in the brain; commonly prescribed SSRIs include Prozac, Lexapro, Celexa, and Paxil. Researchers from the Max Planck Institute in Germany used an MRI machine to look at the gray matter of participants who took SSRIs and those who didn't, and using the images to create 3D maps of certain neural connections.
One thing that surprised the researchers was seeing the changes to the brain that took place after just one dose. "What was really surprising was that the entire brain would light up after only three hours," neuroscientist Dr. Julia Sacher told the Los Angeles Times. "We didn't expect that."
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.

Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
Having this information could help researchers determine if a brain scan could aid psychiatrists in differentiating between patients who do respond to SSRIs and those who don't. Read more about the study at the Los Angeles Times.
Sign up for Today's Best Articles in your inbox
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Catherine Garcia has worked as a senior writer at The Week since 2014. Her writing and reporting have appeared in Entertainment Weekly, The New York Times, Wirecutter, NBC News and "The Book of Jezebel," among others. She's a graduate of the University of Redlands and the Columbia University Graduate School of Journalism.
-
Harvard sues Trump over frozen grant money
Speed Read The Trump administration withheld $2.2 billion in federal grants and contracts after Harvard rejected its demands
By Peter Weber, The Week US
-
Trump tariffs place trucking industry in the crosshairs
IN THE SPOTLIGHT As the White House barrels ahead with its massive tariff project, American truckers are feeling the heat from a global trade war
By Rafi Schwartz, The Week US
-
Trump stands by Hegseth amid ouster reports
Speed Read The president dismissed reports that he was on the verge of firing Defense Secretary Pete Hegseth over a second national security breach
By Rafi Schwartz, The Week US
-
Scientists find hint of alien life on distant world
Speed Read NASA's James Webb Space Telescope has detected a possible signature of life on planet K2-18b
By Peter Weber, The Week US
-
Katy Perry, Gayle King visit space on Bezos rocket
Speed Read Six well-known women went into lower orbit for 11 minutes
By Peter Weber, The Week US
-
Scientists map miles of wiring in mouse brain
Speed Read Researchers have created the 'largest and most detailed wiring diagram of a mammalian brain to date,' said Nature
By Peter Weber, The Week US
-
Scientists genetically revive extinct 'dire wolves'
Speed Read A 'de-extinction' company has revived the species made popular by HBO's 'Game of Thrones'
By Peter Weber, The Week US
-
Dark energy may not doom the universe, data suggests
Speed Read The dark energy pushing the universe apart appears to be weakening
By Peter Weber, The Week US
-
Pharaoh's tomb discovered for first time in 100 years
Speed Read This is the first burial chamber of a pharaoh unearthed since Tutankhamun in 1922
By Peter Weber, The Week US
-
Scientists report optimal method to boil an egg
Speed Read It takes two temperatures of water to achieve and no fancy gadgets
By Peter Weber, The Week US
-
Europe records big leap in renewable energy
Speed Read Solar power overtook coal for the first time
By Peter Weber, The Week US