Experiments hint at possibility of conceiving children with skin cells — not eggs

Successful new research on mice has scientists wondering if in the future, two men could potentially have a child together entirely without the genetic assistance of a woman. While up until this point scientists had assumed it necessary to fertilize an egg with sperm to conceive a baby, the new experiment has shown that it is in fact possible to conceive mice (and potentially human children) using other kinds of cells, such as possibly skin cells, The Independent reports.
"Our work challenges the dogma, held since early embryologists first observed mammalian eggs around 1827 and observed fertilization 50 years later, that only an egg cell fertilized with a sperm cell can result in live mammalian birth," lead scientist Tony Perry told The Independent.
The mouse experiment took "parthenogenote" embryos made by scientists and introduced them to sperm; the cells were changed into normal embryos, resulting in 30 mouse pups — an incredible 24 percent success rate compared to the 1 or 2 percent success from regular cloning. "That finding matters because parthenogenotes are similar to other ordinary cells, like skin cells. Both are mitotic, and if living offspring can be produced from one then it should be possible to create them from the other using the same technique," The Independent writes.
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.

Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
The research could result in the ability for gay biological men to have children with each other, or a man to fertilize his own cells. The research could also help infertile women to have children and aid in the preservation of endangered species whose eggs are often difficult to collect. Many scientists still call these possibilities "speculative and fanciful," and it's true that there is still much research to be done — "but I think, if it is ever possible, one day in the distant future people will look back and say this is where it started," Perry said.
Sign up for Today's Best Articles in your inbox
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Jeva Lange was the executive editor at TheWeek.com. She formerly served as The Week's deputy editor and culture critic. She is also a contributor to Screen Slate, and her writing has appeared in The New York Daily News, The Awl, Vice, and Gothamist, among other publications. Jeva lives in New York City. Follow her on Twitter.
-
ABLE accounts: how they work and who can benefit from them
the explainer These state-administered accounts are available to people with disabilities
By Becca Stanek, The Week US Published
-
James Daunt picks his favourite books
The Week Recommends The founder of Daunt Books and managing director of Waterstones reveals his top five reads
By The Week UK Published
-
Sudoku medium: March 7, 2025
The Week's daily medium sudoku puzzle
By The Week Staff Published
-
New Mexico to investigate death of Gene Hackman, wife
speed read The Oscar-winning actor and his wife Betsy Arakawa were found dead in their home with no signs of foul play
By Peter Weber, The Week US Published
-
Giant schnauzer wins top prize at Westminster show
Speed Read Monty won best in show at the 149th Westminster Kennel Club dog show
By Peter Weber, The Week US Published
-
Beyoncé, Kendrick Lamar take top Grammys
Speed Read Beyoncé took home album of the year for 'Cowboy Carter' and Kendrick Lamar's diss track 'Not Like Us' won five awards
By Peter Weber, The Week US Published
-
The Louvre is giving 'Mona Lisa' her own room
Speed Read The world's most-visited art museum is getting a major renovation
By Peter Weber, The Week US Published
-
Honda and Nissan in merger talks
Speed Read The companies are currently Japan's second and third-biggest automakers, respectively
By Peter Weber, The Week US Published
-
Taylor Swift wraps up record-shattering Eras tour
Speed Read The pop star finally ended her long-running tour in Vancouver, Canada
By Peter Weber, The Week US Published
-
Drake claims illegal boosting, defamation
Speed Read The rapper accused Universal Music of boosting Kendrick Lamar's diss track and said UMG allowed him to be falsely accused of pedophilia
By Rafi Schwartz, The Week US Published
-
'Wicked' and 'Gladiator II' ignite holiday box office
Speed Read The combination of the two movies revitalized a struggling box office
By Peter Weber, The Week US Published