Early Novavax coronavirus vaccine trial produced antibodies in all of its human volunteers

Another vaccine is showing promising results in the fight to find a COVID-19 solution.
Novavax, a Maryland-based company with $1.6 billion federal funding behind its coronavirus vaccine development, released two preliminary studies Tuesday. In one, all of its more than 130 human volunteers produced antibodies to combat the coronavirus, and in another, monkeys developed strong a resistence to the virus.
All of the humans in Novavax's trial may have some form of protection against COVID-19, but 56 of them produced a high level of antibodies without any dangerous side effects, The New York Times notes. Volunteers who had two doses of the vaccine three weeks apart, plus a booster, had the best results. Their antibodies measured approximately four times higher than those in patients who'd recovered from coronavirus, Stat News reports. Still, more than 60 percent of recipients had side effects including pain, headaches, and fatigue. Eight people had to be hospitalized, though their side effects were not life threatening and they were quickly released.
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.

Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
Novavax's vaccines are only in their first phase of study, while other developers have some in a phase three, where large amounts of people receive the vaccine. Still, John Moore, a virologist at Weill Cornell Medicine who was not involved in the studies, told the Times these were some of the most promising vaccine results he has seen yet. "This is the first one I'm looking at and saying, 'Yeah, I'd take that,'" Moore said. Angela Rasmussen, a virologist at Columbia University who was not involved in the studies, cautioned there's no guarantee of safety until a phase three trial compares people who get the vaccine with people who got a placebo. It's still essential this study receives a peer review as well.
Sign up for Today's Best Articles in your inbox
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Kathryn is a graduate of Syracuse University, with degrees in magazine journalism and information technology, along with hours to earn another degree after working at SU's independent paper The Daily Orange. She's currently recovering from a horse addiction while living in New York City, and likes to share her extremely dry sense of humor on Twitter.
-
Today's political cartoons - February 18, 2025
Cartoons Tuesday's cartoons - Zelenskyy excluded, illiberal arts, and more
By The Week US Published
-
How will Keir Starmer pay for greater defence spending?
Today's Big Question Funding for courts, prisons, local government and the environment could all be at risk
By Sorcha Bradley, The Week UK Published
-
Ukraine's mineral riches and Trump's shakedown diplomacy
The Explainer President's demand for half of Kyiv's resources in return for past military aid amounts to 'mafia blackmail tactics' and 'colonialism'
By Harriet Marsden, The Week UK Published
-
Ozempic can curb alcohol cravings, study finds
Speed read Weight loss drugs like Ozempic and Wegovy may also be helpful in limiting alcohol consumption
By Peter Weber, The Week US Published
-
New form of H5N1 bird flu found in US dairy cows
Speed Read This new form of bird flu is different from the version that spread through herds in the last year
By Peter Weber, The Week US Published
-
Microplastics accumulating in human brains, study finds
Speed Read The amount of tiny plastic particles found in human brains increased dramatically from 2016 to 2024
By Peter Weber, The Week US Published
-
FDA approves painkiller said to thwart addiction
Speed Read Suzetrigine, being sold as Journavx, is the first new pharmaceutical pain treatment approved by the FDA in 20 years
By Rafi Schwartz, The Week US Published
-
Study finds possible alternative abortion pill
Speed Read An emergency contraception (morning-after) pill called Ella could be an alternative to mifepristone for abortions
By Peter Weber, The Week US Published
-
California declares bird flu emergency
Speed Read The emergency came hours after the nation's first person with severe bird flu infection was hospitalized
By Rafi Schwartz, The Week US Published
-
Bird flu one mutuation from human threat, study finds
Speed Read A Scripps Research Institute study found one genetic tweak of the virus could enable its spread among people
By Peter Weber, The Week US Published
-
Dark chocolate tied to lower diabetes risk
Speed Read The findings were based on the diets of about 192,000 US adults over 34 years
By Peter Weber, The Week US Published