Paused coronavirus vaccine trials ready to resume

Coronavirus vaccine trials conducted by AstraZeneca and Johnson & Johnson are preparing to resume, the pharmaceutical companies said Friday.

Both studies were put on hold after two volunteers who enrolled in AstraZeneca's vaccine trial developed a possible neurological side effect, and another person enrolled in J&J's study reportedly suffered a stroke. AstraZeneca, which had already restarted its trial in other parts of the world, including the United Kingdom, South Africa, and Brazil, said independent monitoring committees and international regulators agreed it was safe to resume the trial in the U.S, as well. The Food and Drug Administration reportedly did not find the vaccine candidate to be responsible for the neurological symptoms, but the agency was also unable to definitively rule out a link.

Similarly, investigators concluded the J&J volunteer's illness did not appear to be related to the vaccine candidate, although there was "no clear cause" of the incident. Paul Stoffels, the chief scientific officer at J&J, told Stat News the company could begin enrolling patients for the vaccine study — the only major one to test just a single dose — again early next week. Read more at The Washington Post and The Wall Street Journal.

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