Johnson & Johnson says its COVID-19 vaccine is 85 percent effective at preventing severe disease
Johnson & Johnson has unveiled some highly-anticipated data on its single-shot COVID-19 vaccine.
The company on Friday announced its vaccine candidate in a global trial was found to overall be 66 percent effective at preventing moderate to severe COVID-19, but 85 percent effective at preventing severe disease. In the United States, the company said the level of protection against moderate to severe illness was 72 percent, but in Latin America, it was 66 percent effective. It was also 57 percent effective in South Africa, where most of the COVID-19 cases were from the B.1.351 variant.
Johnson & Johnson's data had been particularly anticipated because, unlike the vaccines from Pfizer and Moderna that have been approved in the United States, this candidate only requires one shot. The overall 66 percent efficacy rate wasn't as high as with either of those vaccines, which were each found to be about 95 percent effective, but that's still above the 50 percent level the FDA requires.
The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.
Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
University of Wisconsin School of Medicine and Public Health vaccine expert Jonathan Temte also told The Washington Post the Johnson & Johnson vaccine could still be a "game changer," especially since it can be stored at refrigerator temperature.
"Back in July and August, I was hoping we would see a vaccine that was 60 percent effective — in my mind, that would be great," Temte told the Post. "And now we have had two that have hit the ball out of the park and set expectations spectacularly high, and that's not fair because we don't need a home run all the times we're up to bat."
Johnson & Johnson also noted that in the the trial, the vaccine provided "complete protection against COVID-related hospitalization and death." The company plans to file with the Food and Drug Administration for emergency authorization within a week, The Associated Press reports, and it says it "expects to have product available to ship immediately following authorization."
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Brendan worked as a culture writer at The Week from 2018 to 2023, covering the entertainment industry, including film reviews, television recaps, awards season, the box office, major movie franchises and Hollywood gossip. He has written about film and television for outlets including Bloody Disgusting, Showbiz Cheat Sheet, Heavy and The Celebrity Cafe.
-
FDA OKs generic abortion pill, riling the rightSpeed Read The drug in question is a generic version of mifepristone, used to carry out two-thirds of US abortions
-
RFK Jr. vaccine panel advises restricting MMRV shotSpeed Read The committee voted to restrict access to a childhood vaccine against chickenpox
-
Texas declares end to measles outbreakSpeed Read The vaccine-preventable disease is still spreading in neighboring states, Mexico and Canada
-
RFK Jr. shuts down mRNA vaccine funding at agencySpeed Read The decision canceled or modified 22 projects, primarily for work on vaccines and therapeutics for respiratory viruses
-
Measles cases surge to 33-year highSpeed Read The infection was declared eliminated from the US in 2000 but has seen a resurgence amid vaccine hesitancy
-
Kennedy's vaccine panel signals skepticism, changeSpeed Read RFK Jr.'s new vaccine advisory board intends to make changes to the decades-old US immunization system
-
Kennedy ousts entire CDC vaccine advisory panelspeed read Health Secretary RFK Jr. is a longtime anti-vaccine activist who has criticized the panel of experts
-
RFK Jr. scraps Covid shots for pregnant women, kidsSpeed Read The Health Secretary announced a policy change without informing CDC officials



