New treatment restored limited vision to people with degenerative eye disease


Researchers report that a new treatment for retinitis pigmentosa (RP), a previously irreversible degenerative eye disease that affects 2 million people around the world, was able to restore partial vision to patients.
The study was published Monday in the journal Nature Medicine. In people with RP, gene mutations cause the slow deterioration of the eye's rod-shaped photoreceptors, so visual information is no longer delivered to the brain. Led by Dr. José-Alain Sahel, a professor of ophthalmology at Sorbonne University and the University of Pittsburgh, researchers took a closer look at ChrimsonR, a protein that triggers electrical activity and makes cells able to absorb light.
The team wanted to find a way to use ChrimsonR to boost the light sensitivity of the cells in the retina, and they were able to "genetically manipulate a harmless adenovirus so that it carried Chrimson," Time reports. "The virus was then injected into the fluid-filled portion of the eye behind the lens."
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.

Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
One of the trial participants, a 58-year-old man who was diagnosed with RP four decades ago, started the study with the ability to perceive some light. A dose of the altered virus was injected into one of his eyes, and he wore goggles to regulate incoming light so it wasn't too intense. For several months, researchers tested him to see if he could determine which objects were in front of him on a table. He wasn't successful until four months in, and soon he could even detect people and the crosswalk at an intersection.
Sahel believes this could be a permanent solution for vision loss caused by RP, but more research needs to be done on everything from dosing levels to the best time to start treating patients. Read more at Time.
Sign up for Today's Best Articles in your inbox
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Catherine Garcia has worked as a senior writer at The Week since 2014. Her writing and reporting have appeared in Entertainment Weekly, The New York Times, Wirecutter, NBC News and "The Book of Jezebel," among others. She's a graduate of the University of Redlands and the Columbia University Graduate School of Journalism.
-
Elon has his 'Legion.' How will Republicans encourage other Americans to have babies?
Today's Big Question The pronatalist movement finds itself in power
By Joel Mathis, The Week US
-
How to travel with your dog
The Week Recommends These tips will help both of you have a great time
By Catherine Garcia, The Week US
-
'Congress could help by providing federal protections'
Instant Opinion Opinion, comment and editorials of the day
By Justin Klawans, The Week US
-
Scientists find hint of alien life on distant world
Speed Read NASA's James Webb Space Telescope has detected a possible signature of life on planet K2-18b
By Peter Weber, The Week US
-
Katy Perry, Gayle King visit space on Bezos rocket
Speed Read Six well-known women went into lower orbit for 11 minutes
By Peter Weber, The Week US
-
Scientists map miles of wiring in mouse brain
Speed Read Researchers have created the 'largest and most detailed wiring diagram of a mammalian brain to date,' said Nature
By Peter Weber, The Week US
-
Scientists genetically revive extinct 'dire wolves'
Speed Read A 'de-extinction' company has revived the species made popular by HBO's 'Game of Thrones'
By Peter Weber, The Week US
-
Dark energy may not doom the universe, data suggests
Speed Read The dark energy pushing the universe apart appears to be weakening
By Peter Weber, The Week US
-
Life after space: how will Nasa's stranded astronauts cope?
In the Spotlight Sunita 'Suni' Williams and Barry 'Butch' Wilmore are headed back to Earth after nine months on the ISS – but their greatest challenge may still lie ahead
By Harriet Marsden, The Week UK
-
Pharaoh's tomb discovered for first time in 100 years
Speed Read This is the first burial chamber of a pharaoh unearthed since Tutankhamun in 1922
By Peter Weber, The Week US
-
Scientists report optimal method to boil an egg
Speed Read It takes two temperatures of water to achieve and no fancy gadgets
By Peter Weber, The Week US