How an ‘experimental arthritis drug’ could help treat Covid-19
Otilimab given to Manchester man as UK clinical trial kicks off

A new drug developed to treat rheumatoid arthritis may be given to the most seriously ill Covid-19 patients, if a clinical trial now under way in Manchester proves successful.
Farhan Hamid, 41, has become the first British coronavirus patient to receive the drug, called otilimab, as part of a study run by Manchester Royal Infirmary.
“The research aims to establish whether otilimab can treat severe lung disease developed as a result of Covid-19,” says Sky News.
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.

Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
Dr Andy Martin, who is running the trial, said Hamid, from south Manchester, had been enrolled in the study because he was experiencing severe difficulty breathing. The experimental drug could “ease the effect of coronavirus on the lungs, dampening the impact of the virus on the immune system”, Martin explained.
Funded by the drug’s manufacturer, Glaxo SmithKline (GSK), the trial has “been given urgent public health research status by the Department of Health and Social Care”, the Daily Mirror reports.
Hospitals from all over the world, including five in the UK, will eventually take part in the tests, which will involve a total of 800 patients. Trials have already begun in the US.
“Those taking part will be allocated into two groups at random, with half receiving a one-hour, single infusion of otilimab,” says the Daily Mail. The other group will get “placebo intravenous therapy, in addition to standard care”.
Christopher Corsico of GSK said the drug is believed to help patients who are experiencing the most severe reaction to Covid-19.
“We know that some Covid-19 patients experience an overreaction of their immune system - sometimes referred to as cytokine storm - which can lead to hospitalisation or death,” he said.
“We believe that otilimab might be able to help counter or calm this process.”
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Holden Frith is The Week’s digital director. He also makes regular appearances on “The Week Unwrapped”, speaking about subjects as diverse as vaccine development and bionic bomb-sniffing locusts. He joined The Week in 2013, spending five years editing the magazine’s website. Before that, he was deputy digital editor at The Sunday Times. He has also been TheTimes.co.uk’s technology editor and the launch editor of Wired magazine’s UK website. Holden has worked in journalism for nearly two decades, having started his professional career while completing an English literature degree at Cambridge University. He followed that with a master’s degree in journalism from Northwestern University in Chicago. A keen photographer, he also writes travel features whenever he gets the chance.
-
July 15 editorial cartoons
Cartoons Tuesday's political cartoons include the dangers of a deficit, Putin shooting fish in a barrel, Kermit the Frog, and Barack Obama's message to Democrats
-
Mortgage reform: is Rachel Reeves betting the house on City rules shake-up?
Today's Big Question Reforms could create up to 36,000 additional mortgages next year
-
The 'extraordinary' trials of Constance Marten and Mark Gordon
The Explainer Couple claim they were 'misunderstood' after going on the run with newborn baby
-
RFK Jr. scraps Covid shots for pregnant women, kids
Speed Read The Health Secretary announced a policy change without informing CDC officials
-
New FDA chiefs limit Covid-19 shots to elderly, sick
speed read The FDA set stricter approval standards for booster shots
-
How the care industry came to rely on migrant workers
The Explainer Government crackdown on recruiting workers abroad risks deepening care sector crisis, industry leaders warn
-
Could medics' misgivings spell the end of the assisted dying bill?
Today's Big Question The Royal College of Psychiatrists has identified 'serious concerns' with the landmark bill – and MPs are taking notice
-
RFK Jr.: A new plan for sabotaging vaccines
Feature The Health Secretary announced changes to vaccine testing and asks Americans to 'do your own research'
-
Washwood Heath: Birmingham's pioneering neighbourhood health service
In the Spotlight NHS England chair says there is a 'really good argument this is the model for the future'
-
Five years on: How Covid changed everything
Feature We seem to have collectively forgotten Covid’s horrors, but they have completely reshaped politics
-
The UK's first legal drug consumption room
The Explainer 'Potentially transformative moment in UK drugs policy' as The Thistle opens in Glasgow