October 2, 2017

On Monday, the Nobel Assembly at Karolinska Institutet in Sweden awarded the Nobel Prize in Physiology or Medicine to three Americans — Jeffrey C. Hall, Michael Rosbash, and Michael W. Young — for their discoveries on the biological clock that "explain how plants, animals, and humans adapt their biological rhythm so that it is synchronized with the Earth's revolutions."

The three scientists, studying fruit flies, discovered a gene that controls the body's daily biological rhythm, the Nobel committee said, then "they showed that this gene encodes a protein that accumulates in the cell during the night, and is then degraded during the day," subsequently discovering other protein components that makes the biological clock function autonomously. "With exquisite precision, our inner clock adapts our physiology to the dramatically different phases of the day," the Nobel committee said. "The clock regulates critical functions such as behavior, hormone levels, sleep, body temperature, and metabolism. Our wellbeing is affected when there is a temporary mismatch between our external environment and this internal biological clock," and thanks to the trio's research, we now know that "chronic misalignment between our lifestyle and the rhythm dictated by our inner timekeeper is associated with increased risk for various diseases."

"Since the seminal discoveries by the three laureates, circadian biology has developed into a vast and highly dynamic research field, with implications for our health and wellbeing," the Nobel committee said. You can read more about Hall, Rosbash, and Young and their work on the circadian rhythm at the Nobel institute. Peter Weber

10:54 p.m.

With more than 516,000 confirmed coronavirus cases, California has reported the most infections of any state, but Gov. Gavin Newsom (D) on Monday said there is some hope on the horizon.

In June and July, the number of cases in California surged, following an ease in lockdown restrictions. Over the last two weeks, the state saw an average of 121 deaths every day, with 214 reported on Friday — a 21 percent increase over the previous record that had been set on Wednesday, the Los Angeles Times reports.

However, the number of hospitalizations statewide has gone down about 10 percent over two weeks, and ICU admissions have fallen by 5 percent. Newsom also said the state has greatly increased its testing capacity, and the share of positive COVID-19 tests has dropped to 7 percent. This rate is "not where it needs to be, and it's still too high," Newsom said, but it's "good to see this number trending down, not trending up."

Newsom credits the small improvements to people being required to wear masks, social distancing, and the "very, very difficult" decision to shutter bars and prohibit indoor dining. There are 38 counties on the state watchlist, including every county in Southern California and the San Francisco Bay Area, and Newsom said everyone needs to stay vigilant, as "we can quickly find ourselves back to where we were just a few weeks ago, a month ago." The virus, he continued, "is not going away. It's not just going to take Labor Day weekend off. It's not going to take Halloween off, the holidays off." Catherine Garcia

9:27 p.m.

President Trump on Monday evening expressed his displeasure with Nevada state lawmakers voting to automatically send mail-in ballots to all voters, telling reporters he will sue to block the bill.

The legislation was approved on Sunday, and Gov. Stephen Sisolak (D) signed the measure into law on Monday evening. Trump, who in April said mail-in voting "doesn't work out well for Republicans," claimed on Twitter Monday morning that the lawmakers conducted an "illegal late night coup" and the "Post Office could never handle the Traffic of Mail-In Votes without preparation. Using Covid to steal the state. See you in Court!"

During a press conference later in the day, Trump repeated his assertion that the U.S. Post Office does not have the infrastructure necessary to handle an influx of mail-in ballots, and said he plans on having the lawsuit blocking Nevada filed on Tuesday. Trump was asked whether he would issue an executive order on mail-in voting, and responded, "I have the right to do it. We haven't gotten there yet. We'll see what happens."

Several state election officials have said they will expand mail-in voting to keep voters safe during the coronavirus pandemic. Experts say voter fraud is rare, especially when there are proper safety measures in place, and a study released earlier this year found that universal vote-by-mail does not benefit any political party. Catherine Garcia

8:29 p.m.

The Apple fire in Riverside County, California, which has burned more than 26,400 acres and is only five percent contained, was ignited by a malfunctioning diesel vehicle, fire officials announced on Monday.

The California Department of Forestry and Fire Protection said in a statement that on Friday evening, the vehicle released burning carbon from its exhaust system, which sparked the fire in Cherry Valley, an unincorporated town about 75 miles east of Los Angeles. Anyone with any information on the vehicle is asked to contact authorities.

The blaze has spread across hillsides and up the side of Mount San Gorgonio, destroying one home and two outbuildings. Nearly 8,000 people have been evacuated, and so far, no injuries have been reported. There are more than 2,300 firefighters on the scene.

"Much of the fire activity is being driven by the record-low moisture content of the vegetation in the area combined with high temperatures and low relative humidity," fire officials said on Monday afternoon. "These conditions are contributing to active fire behavior both day and night." Catherine Garcia

7:41 p.m.

On Monday, Israeli jets struck several Syrian military targets, including intelligence-collection systems, observation posts, antiaircraft artillery facilities, and command and control centers, the Israeli army announced in a statement.

The army said this was in response to the Israeli military foiling an attack early Sunday, after troops spotted four suspected militants from Syria attempting to drop explosive devices along a security fence in the Golan Heights region; they were fired on by Israeli troops and aircraft and killed.

"The Israel Defense Forces holds the Syrian government responsible for all activities originating from Syrian soil, and will continue operating with determination against any violation of Israeli sovereignty," the army stated.

Last week, Israel said Hezbollah militants attempted to cross into its territory from Lebanon, and Israeli Prime Minister Benjamin Netanyahu said the group's sponsor, Iran, is trying to cause chaos by "entrenching its military in our region." Hezbollah denied being part of the operation. Catherine Garcia

6:41 p.m.

World Health Organization Director-General Tedros Adhanom Ghebreyesus said on Monday he is hopeful that the six coronavirus vaccine candidates now in their third phase of clinical trials will be effective, but warned that there is "no silver bullet at the moment and there might never be."

Until there is an approved vaccine, the world must follow "the basics" of disease control, he said, which involves testing, isolating, tracing, and quarantining, as well as social distancing, regular hand washing, and wearing masks. "The message to people and governments is clear: Do it all," Tedros added.

On Jan. 30, the WHO declared COVID-19 a public health emergency, and at the time "there were fewer than 100 cases and no deaths outside of China," Tedros said. Today, worldwide there are 18.1 million COVID-19 cases, with more than 690,000 people dying of the virus, according to the Johns Hopkins University coronavirus tracker. Catherine Garcia

5:43 p.m.

A Department of Homeland Security intelligence report leaked to The Nation has some experts skeptical of the department's motives.

The report targeted several left-wing American activists whom the department would normally be prohibited from gathering intelligence on unless they had reason to believe the individuals were operating on behalf of a foreign power. The people named in the report, many of whom have identified with far-left causes, do have connections abroad — they traveled to Syria in the past and fought against ISIS alongside Kurdish factions like the YPG, PKK, and the Peshmerga.

The U.S., of course, considers ISIS an enemy, as well, so it may seem surprising that the U.S. government would focus on people who volunteered to fight against the terrorist group, but critics argue the Syria connection could be a front to root out potential antifa members. (Some of the individuals denied membership in antifa, which does not necessarily operate in any organized capacity to begin with.)

The report eventually appears to conclude there is no evidence of a "centralized effort to give marching orders to returning antifa-affiliated" U.S. residents, but either way, the briefing didn't sit well with everyone. "They targeted Americans like they're Al-Qaeda," a former intelligence officer in the department with knowledge of the operations told The Nation. "They were essentially violating people's rights like this was the 60s." Read more at The Nation. Tim O'Donnell

4:31 p.m.

The Philadelphia Phillies and Miami Marlins received some encouraging coronavirus-related news Sunday and are likely return to the field soon, but things aren't going as well for the St. Louis Cardinals.

The Cardinals have had 13 members of their clubhouse — seven players and six staff members — test positive for the coronavirus. The team had its its weekend series against the Milwaukee Brewers postponed, and will no longer travel to Detroit for the next slate of games against the Tigers. That makes them, along with the Marlins, who have had 18 players test positive, and the Phillies, who paused play out of caution but do not appear to have an outbreak, the third team to miss at least a week of baseball games during the young season.

Despite the possibility of cancellation, MLB still isn't planning to pause the season overall, and teams like the Cardinals, Phillies, and Marlins, will seemingly do what they can to make up as many games as possible, even if they don't play a full 60-game season.

While the baseball situation is bleak for St. Louis, the players and staff are — more importantly — in good condition, exhibiting either "light" or no symptoms, general manager John Mozeliak said. Tim O'Donnell

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