A modified polio vaccine is successfully treating deadly brain tumors


Polio may seem out of date in the U.S., but its vaccine may be leading to a new medical breakthrough.
A modified polio vaccine injected into patients' deadly brain tumors helped reverse their "dismal" diagnoses, a report in The New England Journal of Medicine suggests. The survival rate for stage IV gliomas — a common type of brain tumor — is usually less than 20 months, and there's no effective treatment. But some of these tested patients are still alive after six years.
The 61 patients treated with the vaccine saw their conditions plateau after two years, and their 21 percent survival rate stayed constant for another year, per the report. Untreated patients had a 14 percent survival rate at two years and just 4 percent a year later.
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.

Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
Not every patient saw success, but it's a hopeful step in treating these aggressive tumors, NBC News says. The study's leader told NBC the results are "unprecedented," and the team will keep testing to figure out how to make the treatment work for everyone.
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
Kathryn is a graduate of Syracuse University, with degrees in magazine journalism and information technology, along with hours to earn another degree after working at SU's independent paper The Daily Orange. She's currently recovering from a horse addiction while living in New York City, and likes to share her extremely dry sense of humor on Twitter.
-
Anne Hillerman's 6 favorite books with Native characters
Feature The author recommends works by Ramona Emerson, Craig Johnson, and more
-
How Zohran Mamdani's NYC mayoral run will change the Democratic Party
Talking Points The candidate poses a challenge to the party's 'dinosaur wing'
-
Book reviews: '1861: The Lost Peace' and 'Murderland: Crime and Bloodlust in the Time of Serial Killers'
Feature How America tried to avoid the Civil War and the link between lead pollution and serial killers
-
Kennedy ousts entire CDC vaccine advisory panel
speed read Health Secretary RFK Jr. is a longtime anti-vaccine activist who has criticized the panel of experts
-
RFK Jr. scraps Covid shots for pregnant women, kids
Speed Read The Health Secretary announced a policy change without informing CDC officials
-
New FDA chiefs limit Covid-19 shots to elderly, sick
speed read The FDA set stricter approval standards for booster shots
-
US overdose deaths plunged 27% last year
speed read Drug overdose still 'remains the leading cause of death for Americans aged 18-44,' said the CDC
-
Trump seeks to cut drug prices via executive order
speed read The president's order tells pharmaceutical companies to lower prescription drug prices, but it will likely be thrown out by the courts
-
RFK Jr. visits Texas as 2nd child dies from measles
Speed Read An outbreak of the vaccine-preventable disease continues to grow following a decade of no recorded US measles deaths
-
Shingles vaccine cuts dementia risk, study finds
Speed Read Getting vaccinated appears to significantly reduce the chances of developing Alzheimer's and other forms of dementia
-
Measles outbreak spreads, as does RFK Jr.'s influence
Speed Read The outbreak centered in Texas has grown to at least three states and Health Secretary Robert F. Kennedy Jr. is promoting unproven treatments