President Trump and Attorney General Jeff Sessions have become bonafide frenemies, and Sen. Lindsey Graham (R-S.C.) says there's no going back.

Last week, Graham revealed he no longer thinks Sessions should be leading the Justice Department, telling reporters it's time for a "fresh voice" that the president "has faith in." And in a Tuesday Today show appearance, the senator hinted at why he's changed his mind.

Host Savannah Guthrie began by asking why Graham would encourage Trump to fire Sessions, because it appears Trump's "only beef" is that the attorney general recused himself from Special Counsel Robert Mueller's investigation. "It's much deeper than that," Graham cryptically replied.

As for what caused the fracture, well, Graham said he "just won't say on this show, but it's a pretty deep breach." The senator isn't necessarily "asking for [Sessions] to be fired," he assured. But Trump has to "replace [Sessions] with somebody who is highly qualified" and, notably, will "allow Mueller to do his job," Graham said.

Graham's statement marks a big change from a year ago, when he said "there will be holy hell to pay" if Sessions was fired. The senator acknowledged his previous defense of Sessions on Tuesday, saying the attorney general "had to recuse himself ... because he was part of the campaign that's now being investigated." But recusal isn't what caused Sessions and Trump's relationship to fall "beyond repair," Graham said.

Watch all of Graham's mysterious statement on Today. Kathryn Krawczyk

Germany was one of the international stars of the early response to the COVID-19 pandemic last year thanks to a renowned contact tracing system that kept infection rates low, but it's vaccine rollout is not going so well. So far, the country has only administered 6.2 million doses, well below the 21 million in the United Kingdom, which began its drive a few weeks earlier, but has a smaller population.

One of the big issues is how difficult it is to sign up for an appointment in the first place, at least in some regions of the country. Per The Financial Times, the registration portal requires 10-online steps, including a two-step authentication process. For months, the website would also only allow people to sign up for one appointment, even though two doses of the vaccines available in Germany are required for full inoculation, and if everything is booked, there's no waiting list people to notify people when more doses become available. "It's totally amateurish and incredibly inflexible," one German health official told FT.

The jumbled nature of the system is giving some Americans "flashbacks" to the highly-anticipated healthcare.gov launch in 2013, which was tainted by a variety of technical difficulties and an incomplete website design that made it challenging for people to sign up for their health insurance. Read more at The Financial Times. Tim O'Donnell

Former Vice President Mike Pence broke his silence Wednesday with an op-ed in The Daily Signal, criticizing congressional Democrats for their voter reform push and giving new life to former President Donald Trump's baseless claims that the 2020 presidential election was stolen.

Despite being a central target of the mob that breached the Capitol on Jan. 6 because of his refusal to answer former President Donald Trump's call to block the Electoral College, Pence claimed the election was "marked by significant irregularities and numerous instances of officials setting aside election law" and said he shares "the concerns of millions of Americans" about its integrity, suggesting he still hasn't fully broken with Trump on the matter. For many people the show of loyalty was baffling.

That said, Pence never outright called the 2020 vote fraudulent in the piece. Rather, he framed its outcome as uncertain so he could launch into his argument about why Congress should not pass HR 1, the so-called For the People Act, which includes measures such as required early voting and same-day voter registration in every state. Pence called the bill "an unconstitutional power grab" with the sole goal of giving "leftists a permanent, unfair, and unconstitutional advantage in our political system." Read the full op-ed at The Daily Signal. Tim O'Donnell

At 14, Benjamin Kagan isn't old enough to get the coronavirus vaccine — but he can help those who are eligible secure appointments.

Due to a limited number of appointments, getting signed up has been hard for most people, and it's even more daunting for those who don't have access to a computer or have a slower internet connection. After making appointments for his grandparents, Kagan, a Chicago resident, was inspired last month to start Chicago Vaccine Angels, a group where volunteers secure appointments for people in need of assistance.

It hasn't been easy, the tech-savvy high schooler said. Kagan has to be on his computer at midnight, ready to get in a virtual line, and "it's incredibly complicated to navigate even for myself," he told CBS Chicago, adding, "If you're not on the ball and getting them as soon as they are released, they're gone." It's worth it, though — since launching Chicago Vaccine Angels, Kagan has helped more than 119 people, mostly seniors, get appointments. Catherine Garcia

After interviewing 79 witnesses and reviewing numerous documents, the Department of Defense inspector general has issued a review of the time Rep. Ronny Jackson (R-Texas) spent as physician to the president, finding that Jackson made inappropriate comments about a female subordinate and drank alcohol while on trips with the president, violating policy.

CNN obtained a copy of the report on Tuesday, a day before its expected release. Jackson, who served as the top White House doctor during the Obama and Trump administrations, was elected in November to represent Texas' 13th Congressional District, and is on the House Armed Services subcommittee. The investigation into his conduct began in 2018, and the report says that the probe was "limited in scope and unproductive" because former President Donald Trump's White House counsel demanded on being present during all interviews with White House Medical Unit employees.

The report states 56 of the witnesses who worked with Jackson said they "personally experienced, saw, or heard about him yelling, screaming, cursing, or belittling subordinates." He was described as a "dictator," "control freak," and "crappy manager," and only 13 witnesses had anything positive to say about him, CNN reports.

While on trips with the president, the White House physician is not allowed to drink for 24 hours before the president's arrival until two hours after the president leaves. Witnesses said they observed Jackson drinking during two overseas trips with former President Barack Obama — in Manila in 2014 and in Bariloche, Argentina, in 2016. In Manila, witnesses said Jackson was intoxicated and made lewd comments about a female subordinate, with one person stating they also spotted him "pounding" on the door to her room while saying "I need you" and "I need you to come to my room."

In a statement, Jackson told CNN the report was politically motivated, and accused Democrats of using it "to repeat and rehash untrue attacks on my integrity." He also denied "any allegation that I consumed alcohol while on duty." Catherine Garcia

More than 300 years after it was mailed, a letter sent from one cousin to another in the Netherlands has finally been opened — virtually.

Jana Dambrogio, a conservator with the Massachusetts Institute of Technology Libraries, told NPR that before the gummed envelope was invented in the 1830s, people would secure their letters via "letterlocking," using intricate folds, creases, slits, and holes to transform the piece of paper into a package. While some archivists have used scissors to cut locked letters, Dambrogio worried about what is lost "when we open the unopened."

With a team of researchers, Dambrogio was able to take a locked letter and read it, without disturbing anything. The letter, written in 1697, was found in The Hague in an old postmaster's trunk. Inks at that time contained high amounts of metal, so the team used an X-ray scanner that can create 3D images of teeth to make a 3D image of the letter. The writing showed up "as a very bright region on the scan," like a bone would appear on an X-ray, Amanda Ghassaei of Adobe Research told NPR.

Because it was folded so many times, the letter had several layers close together, making the words look jumbled. The team had to "find a way to manipulate that data and actually virtually unfold it so that we could get it into a flat state," Ghassaei said. Success came after the researchers used a brute-force algorithm, and they discovered that the letter was sent to request an official death certificate for a relative.

The folding pattern included an arrow shape, and is "quite beautiful," Dambrogio told NPR. She finds it "thrilling" that the note can be read "without tampering with the letter packet, leaving it to study as an unopened object." Catherine Garcia

The Senate confirmed Cecilia Rouse on Tuesday to become chair of the White House Council of Economic Advisers.

Rouse, a labor economist and former dean of the Princeton School of Public and International Affairs, is the first Black person to serve in the role. She was confirmed with a vote of 95-4.

Rouse served on the council during the first Obama administration, in the wake of the Great Recession. During her confirmation hearing, Rouse said economists often "focus on average outcomes instead of examining a range of outcomes. One of my priorities as chair will be to try to understand how policies will impact all in our country, as we strive to ensure the economy works for everyone."

There are too many people who have "slipped through our frayed safety net into hardship and hopelessness," Rouse added. "And structural inequities that have always existed within our economy have not just been exposed, but exacerbated, their impact more devastating than ever before." Catherine Garcia