Health & Science

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A blood test for Alzheimer’s

An experimental new blood test may soon make it possible for people to know they will develop Alzheimer’s disease years before any telltale symptoms have surfaced. The simple procedure determines the levels of 10 lipids in the blood, which at low levels have been found to signal, with more than 90 percent accuracy, the onset of Alzheimer’s within three years. “This is a potential game changer,” Georgetown University neurologist Howard Federoff, who helped develop the test, tells CNN.com. Currently, there is no reliable test that predicts the onset of Alzheimer’s. To develop the new test, researchers took blood samples from 525 people ages 70 and older and then tracked their cognitive health for five years. By comparing the samples from 53 participants who developed mild cognitive impairment or Alzheimer’s against samples from 53 participants who did not, they identified 10 lipids, or fats, that distinguished the afflicted group’s blood samples. They then found the same lipids in samples from 41 other participants. More research would be needed to develop the test so that it could be used outside clinical trials, and since there’s still no cure or effective drug treatment, many people might question the point of taking one. “I think it’s a very personal decision,” Federoff says. “Patients and their families would have to be counseled.”

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