The CEO of Pfizer is expressing confidence in the company's coronavirus vaccine candidate, which he says could potentially receive approval from the FDA this October.
Pfizer CEO Albert Bourla spoke with Time this week after the pharmaceutical company recently released the first clinical data on its COVID-19 candidate, which showed it generated neutralizing antibodies at levels 1.8 to 2.8-times the levels found in patients who recovered from COVID-19. There were, however, some side effects including fevers.
"What we learned is that this vaccine can neutralize the virus," Bourla told Time. "...For me, it was the moment when I saw the data, plus many other data that we haven't published yet, [that] made me say that until now I was thinking if we have a vaccine. Now I'm discussing when we're going to have a vaccine."
Bourla added that "we have a lot of indications that make me feel that really it should make it," noting that it won't be until "we have the final study" that it's clear whether the vaccine candidate works but saying that this answer should come around September.
"So for a potential approval in October, if we are lucky," he said. "It's feasible."
If that happens, Bourla says "we will have already manufactured doses that will be readily available" as soon as the FDA approval comes. In announcing its recent data, Pfizer said it's looking to "manufacture up to 100 million doses by the end of 2020 and potentially more than 1.2 billion doses by the end of 2021." Brendan Morrow
With more than 516,000 confirmed coronavirus cases, California has reported the most infections of any state, but Gov. Gavin Newsom (D) on Monday said there is some hope on the horizon.
In June and July, the number of cases in California surged, following an ease in lockdown restrictions. Over the last two weeks, the state saw an average of 121 deaths every day, with 214 reported on Friday — a 21 percent increase over the previous record that had been set on Wednesday, the Los Angeles Times reports.
However, the number of hospitalizations statewide has gone down about 10 percent over two weeks, and ICU admissions have fallen by five percent. Newsom also said the state has greatly increased its testing capacity, and the share of positive COVID-19 tests has dropped to seven percent. This rate is "not where it needs to be, and it's still too high," Newsom said, but it's "good to see this number trending down, not trending up."
Newsom credits the small improvements to people being mandated to wear masks, social distancing, and the "very, very difficult" decision to shutter bars and prohibit indoor dining. There are 38 counties on the state watchlist, including every county in Southern California and the San Francisco Bay Area, and Newsom said everyone needs to stay vigilant, as "we can quickly find ourselves back to where we were just a few weeks ago, a month ago." The virus, he continued, "is not going away. It's not just going to take Labor Day weekend off. It's not going to take Halloween off, the holidays off." Catherine Garcia
President Trump on Monday evening expressed his displeasure with Nevada state lawmakers voting to automatically send mail-in ballots to all voters, telling reporters he will sue to block the bill.
The legislation was approved on Sunday, and Gov. Stephen Sisolak (D) signed the measure into law on Monday evening. Trump, who in April said mail-in voting "doesn't work out well for Republicans," claimed on Twitter Monday morning that the lawmakers conducted an "illegal late night coup" and the "Post Office could never handle the Traffic of Mail-In Votes without preparation. Using Covid to steal the state. See you in Court!"
During a press conference later in the day, Trump repeated his assertion that the U.S. Post Office does not have the infrastructure necessary to handle an influx of mail-in ballots, and said he plans on having the lawsuit blocking Nevada filed on Tuesday. Trump was asked whether he would issue an executive order on mail-in voting, and responded, "I have the right to do it. We haven't gotten there yet. We'll see what happens."
Several state election officials have said they will expand mail-in voting to keep voters safe during the coronavirus pandemic. Experts say voter fraud is rare, especially when there are proper safety measures in place, and a study released earlier this year found that universal vote-by-mail does not benefit any political party. Catherine Garcia
The Apple fire in Riverside County, California, which has burned more than 26,400 acres and is only five percent contained, was ignited by a malfunctioning diesel vehicle, fire officials announced on Monday.
The California Department of Forestry and Fire Protection said in a statement that on Friday evening, the vehicle released burning carbon from its exhaust system, which sparked the fire in Cherry Valley, an unincorporated town about 75 miles east of Los Angeles. Anyone with any information on the vehicle is asked to contact authorities.
The blaze has spread across hillsides and up the side of Mount San Gorgonio, destroying one home and two outbuildings. Nearly 8,000 people have been evacuated, and so far, no injuries have been reported. There are more than 2,300 firefighters on the scene.
"Much of the fire activity is being driven by the record-low moisture content of the vegetation in the area combined with high temperatures and low relative humidity," fire officials said on Monday afternoon. "These conditions are contributing to active fire behavior both day and night." Catherine Garcia
On Monday, Israeli jets struck several Syrian military targets, including intelligence-collection systems, observation posts, antiaircraft artillery facilities, and command and control centers, the Israeli army announced in a statement.
The army said this was in response to the Israeli military foiling an attack early Sunday, after troops spotted four suspected militants from Syria attempting to drop explosive devices along a security fence in the Golan Heights region; they were fired on by Israeli troops and aircraft and killed.
"The Israel Defense Forces holds the Syrian government responsible for all activities originating from Syrian soil, and will continue operating with determination against any violation of Israeli sovereignty," the army stated.
Last week, Israel said Hezbollah militants attempted to cross into its territory from Lebanon, and Israeli Prime Minister Benjamin Netanyahu said the group's sponsor, Iran, is trying to cause chaos by "entrenching its military in our region." Hezbollah denied being part of the operation. Catherine Garcia
World Health Organization Director-General Tedros Adhanom Ghebreyesus said on Monday he is hopeful that the six coronavirus vaccine candidates now in their third phase of clinical trials will be effective, but warned that there is "no silver bullet at the moment and there might never be."
Until there is an approved vaccine, the world must follow "the basics" of disease control, he said, which involves testing, isolating, tracing, and quarantining, as well as social distancing, regular hand washing, and wearing masks. "The message to people and governments is clear: Do it all," Tedros added.
On Jan. 30, the WHO declared COVID-19 a public health emergency, and at the time "there were fewer than 100 cases and no deaths outside of China," Tedros said. Today, worldwide there are 18.1 million COVID-19 cases, with more than 690,000 people dying of the virus, according to the Johns Hopkins University coronavirus tracker. Catherine Garcia