How many people need to be vaccinated to get back to normal?
Herd immunity percentage is not a ‘magic threshold’
Clinical tests from the various Covid-19 vaccine candidates last year offered a first glimmer of hope of a return to normality - but only now can the real-world impact of the jabs be assessed.
As countries worldwide race to inoculate populations against the coronavirus, the rollouts are beginning to affect rates of infections and related deaths. Here is what we can learn from the latest data on the main Covid vaccines.
1. Oxford-AstraZeneca vaccine
The Oxford-AstraZeneca vaccine appears to cut Covid infections by two-thirds according to the first “real-world data” on the impact of the jab, The Telegraph reports.
Subscribe to The Week
Escape your echo chamber. Get the facts behind the news, plus analysis from multiple perspectives.
Sign up for The Week's Free Newsletters
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
From our morning news briefing to a weekly Good News Newsletter, get the best of The Week delivered directly to your inbox.
The newly published figures - which will influence Boris Johnson’s lockdown exit roadmap - suggest that “just one dose of either the Oxford or Pfizer vaccines has such an effect on all age groups”, the paper says. And latest data also show that “Covid cases are falling most rapidly among the oldest, with care home outbreaks almost halving in a week”.
Meanwhile, a study by Public Health Scotland has found that by the fourth week after receiving the initial dose, the Oxford vaccine reduces the risk of hospitalisation with Covid by a “whopping” 94%, reports the Daily Mirror. The statistics were gathered between 8 December and 15 February, when 1.14 million vaccines were administered in Scotland, and give “great reasons to be optimistic for the future”, said lead researcher Professor Aziz Sheikh, director of the University of Edinburgh’s Usher Institute.
In an article published in The Spectator in January, John Roberts of the Covid-19 Actuary Response Group predicted that if the UK’s vaccine campaign went to plan, the country would see a 15% reduction in Covid cases by mid-March. Hospital admission would fall by 60%, while Covid-related deaths would drop by 88%, Roberts wrote.
Will the Oxford Covid vaccine be the true game-changer?
Sign up for Today's Best Articles in your inbox
A free daily email with the biggest news stories of the day – and the best features from TheWeek.com
2. Pfizer-BioNTech vaccine
Although Israel is still in lockdown, a significant drop in coronavirus cases in the Middle Eastern country is being attributed largely to the speedy rollout of vaccines across the nation. The BBC reports that “the fall appears to be most pronounced in older people and areas furthest ahead in their immunisation efforts”.
Figures released at the start of February by the Israeli Ministry of Health show that just 0.07% (531) of almost 750,000 people aged over 60 who had been fully vaccinated had tested positive for Covid after getting the jab. And only 38 of those who were infected were hospitalised.
The Pfizer-BioNTech jab accounts for the majority of the vaccinations administered in Israel to date. According to Pfizer, research has found that the efficacy of the vaccine is “consistent across age” groups, providing 94% protection in patients over 64 - just 1% lower than the overall efficacy rate among all test subjects.
Latest figures from Public Health Scotland also indicate that the jab is beginning to have an impact in the UK. The same study that revealed encouraging results for the Oxford jab also found that the Pfizer vaccine caused a 85% reduction in hospitalisations within four weeks of the first dose being administered.
How does the Pfizer coronavirus vaccine work?
3. Moderna vaccine
Moderna’s long-awaited coronavirus vaccine candidate was found to be 94.5% effective in early clinical results published in November.
The jab is being widely used in the US, where a study of 62,138 patients between 1 December and 8 February found that the vaccine was 53.6% effective within the first seven days of the first dose being administered, rising to 88.7% after six weeks.
Among the vaccinated patients who did test positive for Covid after receiving the jab, the 14-day hospitalisation rate was 3.7%, compared with 9.2% among those who had not been inoculated.
Moderna has had effective Covid-19 vaccine since January
4. Janssen vaccine
The single-shot Covid vaccine developed by healthcare giant Johnson & Johnson is 85% effective at preventing the most serious coronavirus symptoms after a single dose, according to trials data published in late January.
The company said that the trials - conducted in several countries - also showed that the vaccine was 66% effective at preventing moderate to severe illness.
South Africa may provide the first real-world data on the impact of the Janssen vaccine, after the country began rolling out the jab its health care workers last week. Johnson & Johnson is awaiting Conditional Marketing Authorisation in the EU and has also applied for Emergency Use Authorisation in the US.
The UK has already ordered 30 million doses of the vaccine, which is pending approval by the Medicines and Healthcare products Regulatory Agency.
Janssen’s single-shot Covid-19 vaccine 85% effective
-
The Duchy Files: how bad is the scandal for King Charles?
Today's Big Question Making millions in rent from the NHS and armed forces a 'PR disaster' for royal family
By The Week UK Published
-
'A stark choice'
Today's Newspapers A roundup of the headlines from the US front pages
By The Week Staff Published
-
The Vietnamese migrants crossing the Channel
The Explainer 2024 has seen a surge in the numbers of Vietnamese migrants making the illegal passage into the UK
By Richard Windsor, The Week UK Published
-
Long Covid: study shows damage to brain's 'control centre'
The Explainer Research could help scientists understand long-term effects of Covid-19 as well as conditions such as MS and dementia
By The Week UK Published
-
Israel, UN agree to Gaza pauses for polio vaccinations
Speed Read Gaza's first case of polio in 25 years was confirmed last week in a 10-month-old boy who is now partially paralyzed
By Rafi Schwartz, The Week US Published
-
FDA OKs new Covid vaccine, available soon
Speed read The CDC recommends the new booster to combat the widely-circulating KP.2 strain
By Peter Weber, The Week US Published
-
Mpox: how dangerous is new health emergency?
Today's Big Question Spread of potentially deadly sub-variant more like early days of HIV than Covid, say scientists
By The Week UK Published
-
What is POTS and why is it more common now?
The explainer The condition affecting young women
By Devika Rao, The Week US Published
-
Brexit, Matt Hancock and black swans: five takeaways from Covid inquiry report
The Explainer UK was 'unprepared' for pandemic and government 'failed' citizens with flawed response, says damning report
By Harriet Marsden, The Week UK Published
-
Should masks be here to stay?
Talking Points New York Governor Kathy Hochul proposed a mask ban. Here's why she wants one — and why it may not make sense.
By Anya Jaremko-Greenwold, The Week US Published
-
Covid might be to blame for an uptick in rare cancers
The explainer The virus may be making us more susceptible to certain cancers
By Devika Rao, The Week US Published